Publication Name	World Journal of Transplantation
Manuscript ID	22007
Country	United States

Received	2015-08-06 08:54
Peer-Review Started	2015-08-07 15:20
To Make the First Decision	2015-10-08 16:39
Return for Revision	2015-10-16 16:09
Revised	2015-10-28 23:38
Second Decision	2015-12-17 18:39
Accepted by Journal Editor-in-Chief	2015-12-19 00:08
Accepted by Executive Editor-in-Chief	2016-01-04 17:06
Articles in Press	2016-01-04 17:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-02 19:08
Publish the Manuscript Online	2016-03-18 14:28

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Minireviews
Article Title	Overview of extended release tacrolimus in solid organ transplantation
Manuscript Source	Invited Manuscript
All Author List	Neha Patel, Abigail Cook, Elizabeth Greenhalgh, Megan A Rech, Joshua Rusinak and Lynley Heinrich
Funding Agency and Grant Number
Corresponding Author	Neha Patel, PharmD, BCPS, Department of Pharmacy, Loyola Medical Center, 2160 S. First Ave., Maywood, IL 60153, United States. paten@musc.edu
Key Words	Tacrolimus; Extended release tacrolimus; Pharmacokinetics; Pharmacoeconomics; Solid-organ transplant
Core Tip	Tacrolimus is an immunosuppressive agent to prevent and treat allograft rejection in solid organ transplant recipients. An extended release tacrolimus formulation known as Astagraf XL is now available which allows for once-daily dosing, with the potential to improve adherence. Both tacrolimus formulations have demonstrated comparable steady-state systemic tacrolimus exposure in de novo kidney and liver transplant recipients. The following review will address the pharmacokinetics of extended release tacrolimus, the data in solid-organ transplantation and the pha-macoeconomic considerations of extended release tacrolimus compared to twice daily tacrolimus.
Publish Date	2016-03-18 14:28
Citation	Patel N, Cook A, Greenhalgh E, Rech MA, Rusinak J, Heinrich L. Overview of extended release tacrolimus in solid organ transplantation. World J Transplant 2016; 6(1): 144-154
URL	http://www.wjgnet.com/2220-3230/full/v6/i1/144.htm
DOI	http://dx.doi.org/10.5500/wjt.v6.i1.144

Full Article (PDF)	WJT-6-144.pdf
Full Article (Word)	WJT-6-144.doc
Manuscript File	22007-Review.docx
Answering Reviewers	22007-Answering reviewers.pdf
Audio Core Tip	22007-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22007-Conflict-of-interest statement.pdf
Copyright License Agreement	22007-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22007-Language certificate.pdf
Peer-review Report	22007-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22007-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22007-Scientific misconduct check.pdf
Scientific Editor Work List	22007-Scientific editor work list.pdf