Publication Name	World Journal of Gastroenterology
Manuscript ID	2202
Country	China

Received	2013-02-06 08:57
Peer-Review Started	2013-02-07 14:17
To Make the First Decision	2013-03-04 13:51
Return for Revision	2013-03-11 15:44
Revised
Second Decision	2013-04-10 16:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-11 05:09
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-05-08 10:24
Publish the Manuscript Online	2013-05-14 16:05

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	MAWBP and MAWD inhibit proliferation and invasion in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Dong-Mei Li, Jun Zhang, Wen-Mei Li, Jian-Tao Cui, Yuan-Ming Pan, Si-Qi Liu, Rui Xing and You-Yong Lu
Funding Agency and Grant Number	Funding Agency Grant Number National Bio-Tech 863 Program 2006AA02A402 National Natural Science Foundation of China 30901717
Corresponding Author	Rui Xing, PhD, Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital/Institute, No. 52, Fucheng Road, Haidian District, Beijing 100142, China. sherry19820420@hotmail.com
Key Words	Gastric cancer; Mitogen-activated protein kinase activator with WD40 repeats binding protein; Mitogen-activated protein kinase activator with WD40 repeats; Invasion; Transforming growth factor-β; Epithelial-mesenchymal transition
Core Tip	Our previous study revealed that mitogen-activated protein kinase activator with WD40 repeats (MAWD) and MAWD binding protein (MAWBP), acting as a complex, were differentially expressed in gastric cancer (GC) tissues compared with that in normal gastric tissues. The present study provided direct evidence that MAWBP and MAWD inhibited proliferation and migration of GC cells. Importantly, interaction of MAWBP and MAWD influenced expression of epithelial-mesenchymal transition (EMT) markers induced by transforming growth factor (TGF)-β1 in GC cells. It indicated that coexpression of MAWBP and MAWD inhibited TGF-β1-induced EMT, thus suppressing EMT-aided GC malignant progression.
Publish Date	2013-05-14 16:05
Citation	Li DM, Zhang J, Li WM, Cui JT, Pan YM, Liu SQ, Xing R, Lu YY. MAWBP and MAWD inhibit proliferation and invasion in gastric cancer. World J Gastroenterol 2013; 19(18): 2781-2792
URL	http://www.wjgnet.com/1007-9327/full/v19/i18/2781.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i18.2781

Full Article (PDF)	WJG-19-2781.pdf
Manuscript File	2202-Review.doc
Answering Reviewers	2202-Answering reviewers.pdf
Copyright License Agreement	2202-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics certification-LYY.pdf
Non-Native Speakers of English Editing Certificate	2202-Language certificate.pdf
Peer-review Report	2202-Peer review.pdf
Scientific Editor Work List	2202-Scientific editor work list.doc