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2/2/2016 6:35:00 PM | Browse: 224 | Download: 323
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 22024
Country of Manuscript Source United Kingdom
Received
2015-08-08 13:34
Peer-Review Started
2015-08-11 16:15
To Make the First Decision
2015-09-16 13:59
Return for Revision
2015-09-22 10:12
Revised
2015-10-12 18:08
Second Decision
2015-11-30 09:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-12-11 16:44
Articles In Press
2015-12-11 16:44
Publication Fee Transferred
Edit the Manuscript by Languag Editor
Typeset the Manuscript
2016-01-29 16:06
Publish the Manuscript Online
2016-02-02 18:35
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Oncology
Manuscript Type Review
Article Title Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?
Manuscript Source Invited Manuscript
All Author List Kiruthikah Thillai, Paul Ross and Debashis Sarker
Funding Agency and Grant Number
Funding Agency Grant Number
Department of Health via the National Institute for Health Research Biomedical Research Centre award to Guy’s and St Thomas’ NHS Foundation Trust in partnership with King’s College London and King’s College Hospital NHS Foundation Trust
Correspondence To Dr. Debashis Sarker, Division of Cancer Studies, King’s College London, Guy’s Hospital Campus, Great Maze Pond, London Bridge, London SE1 9RT, United Kingdom. debashis.sarker@kcl.ac.uk
Keywords Hepatocellular carcinoma; Molecular targets; Genomics; Sorafenib; Tyrosine kinase inhibitors
Core Tip This review discusses the current drug therapy landscape for advanced hepatocellular carcinoma, in particular the reasons for failure of several clinical trials of molecularly targeted therapy and future directions of research to address these problems.
Publish Date 2016-02-02 18:35
Citation Thillai K, Ross P, Sarker D. Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis? World J Gastrointest Oncol 2016; 8(2): 173-185
Url http://www.wjgnet.com/1948-5204/full/v8/i2/173.htm
DOI http://dx.doi.org/10.4251/wjgo.v8.i2.173
Full Article (PDF) WJGO-8-173.pdf
Full Article (Word) WJGO-8-173.doc
Revised Manuscript 22024-Review.docx
Peer-review Report 22024-Peer-review(s).pdf
Answering Reviewers 22024-Answering reviewers.pdf
Scientific Misconduct Check 22024-Scientific misconduct check.pdf
Scientific Editor Work List 22024-Scientific editor work list.pdf
Audio 22024-Audio core tip.mp3
Conflict-of-Interest Statement 22024-Conflict-of-interest statement.pdf
Copyright Assignment 22024-Copyright assignment.pdf