Publication Name	World Journal of Radiology
Manuscript ID	22131
Country	United States

Received	2015-08-14 12:01
Peer-Review Started	2015-08-16 08:10
To Make the First Decision	2015-10-27 11:04
Return for Revision	2015-11-07 15:11
Revised	2015-11-17 06:34
Second Decision	2016-01-25 14:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-02-16 09:06
Articles in Press	2016-02-16 09:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-30 19:04
Publish the Manuscript Online	2016-04-19 16:30

ISSN	1949-8470 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Quantitative study of prostate cancer using three dimensional fiber tractography
Manuscript Source	Invited Manuscript
All Author List	Sandeep Hedgire, Alexey Tonyushkin, Aoife Kilcoyne, Jason A Efstathiou, Peter F Hahn and Mukesh Harisinghani
Funding Agency and Grant Number	Funding Agency Grant Number Mac Erlaine Research Scholarship, St. Vincents University Hospital, Dublin, Ireland to Dr. Aoife Kilcoyne
Corresponding Author	Sandeep Hedgire, MD, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, United States. hedgire.sandeep@mgh.harvard.edu
Key Words	Prostate cancer; Tract density; Diffusion tensor imaging; Tractography; Magnetic resonance imaging
Core Tip	Our study identified 24 men with biopsy proven prostate cancer. These patients underwent prostate magnetic resonance imaging with an endorectal coil on a 1.5 T scanner. Software was used to generate a diffusion tensor imaging (DTI) map and 3D fiber tracts. DTI tractography demonstrated rich fiber tract anatomy with tract heterogeneity. Tract density may represent a new biomarker to distinguish tumor from normal tissue.
Publish Date	2016-04-19 16:30
Citation	Hedgire S, Tonyushkin A, Kilcoyne A, Efstathiou JA, Hahn PF, Harisinghani M. Quantitative study of prostate cancer using three dimensional fiber tractography. World J Radiol 2016; 8(4): 397-402
URL	http://www.wjgnet.com/1949-8470/full/v8/i4/397.htm
DOI	http://dx.doi.org/10.4329/wjr.v8.i4.397

Full Article (PDF)	WJR-8-397.pdf
Full Article (Word)	WJR-8-397.doc
Manuscript File	22131-Review.docx
Answering Reviewers	22131-Answering reviewers.pdf
Audio Core Tip	22131-Audio core tip.mp3
Biostatistics Review Certificate	22131-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	22131-Conflict-of-interest statement.pdf
Copyright License Agreement	22131-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150814115945.doc
Institutional Review Board Approval Form or Document	22131-Institutional review board statement.pdf
Peer-review Report	22131-Peer-review(s).pdf
Scientific Misconduct Check	22131-Scientific misconduct check.pdf
Scientific Editor Work List	22131-Scientific editor work list.pdf