Publication Name	World Journal of Gastroenterology
Manuscript ID	22204
Country	China

Received	2015-09-11 08:57
Peer-Review Started	2015-09-13 18:18
To Make the First Decision	2015-11-11 16:11
Return for Revision	2015-11-11 16:49
Revised	2015-11-16 13:55
Second Decision	2015-11-24 17:52
Accepted by Journal Editor-in-Chief	2015-11-27 07:37
Accepted by Company Editor-in-Chief	2015-12-08 17:14
Articles in Press	2015-12-08 17:14
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-01-20 18:18
Typeset the Manuscript	2016-03-02 11:49
Publish the Manuscript Online	2016-03-23 16:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Pathology
Manuscript Type	Frontier
Article Title	Latest developments in precancerous lesions of hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Zhao-Shan Niu, Xiao-Jun Niu, Wen-Hong Wang and Jing Zhao
Funding Agency and Grant Number
Corresponding Author	Zhao-Shan Niu, MD, Laboratory of Micromorphology, Medical College of Qingdao University, Room 201, Building Boya, No. 308 Ningxia Road, Qingdao 266071, Shandong Province, China. niumiao1993@hotmail.com
Key Words	Hepatocellular carcinoma; Precancerous lesions; High-grade dysplastic nodule; Large cell change; Small cell change
Core Tip	The identification and characteristics of hepatic precancerous lesions may serve as early clues to malignant transformation. Over the last 10 years, studies of precancerous lesions have resulted in signi-ficant progress, especially in molecular biology and imaging technology. Based on our extensive review of the relevant literature, this article focuses on evidence that supports the precancerous nature of dysplastic foci and dysplastic nodules from a clinical, pathological, molecular genetic and radiological point of view.
Publish Date	2016-03-23 16:22
Citation	Niu ZS, Niu XJ, Wang WH, Zhao J. Latest developments in precancerous lesions of hepatocellular carcinoma. World J Gastroenterol 2016; 22(12): 3305-3314
URL	http://www.wjgnet.com/1007-9327/full/v22/i12/3305.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i12.3305

Full Article (PDF)	WJG-22-3305.pdf
Full Article (Word)	WJG-22-3305.doc
Manuscript File	22204-Review.doc
Answering Reviewers	22204-Answering reviewers.pdf
Audio Core Tip	22204-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22204-Conflict-of-interest statement.pdf
Copyright License Agreement	22204-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22204-Language certificate.pdf
Peer-review Report	22204-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22204-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22204-Scientific misconduct check.pdf
Scientific Editor Work List	22204-Scientific editor work list.pdf