Publication Name	World Journal of Psychiatry
Manuscript ID	22223
Country	United Kingdom

Received	2015-08-21 08:00
Peer-Review Started	2015-08-22 20:23
To Make the First Decision	2015-10-27 11:14
Return for Revision	2015-10-30 15:43
Revised	2015-11-14 00:00
Second Decision	2016-01-12 16:17
Accepted by Journal Editor-in-Chief	2016-01-12 21:16
Accepted by Executive Editor-in-Chief	2016-01-22 15:57
Articles in Press	2016-01-22 15:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-03 14:24
Publish the Manuscript Online	2016-03-16 12:23

ISSN	2220-3206 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Psychiatry
Manuscript Type	Review
Article Title	Sex differences in cognitive impairment in Alzheimer’s disease
Manuscript Source	Invited Manuscript
All Author List	Keith R Laws, Karen Irvine and Tim M Gale
Funding Agency and Grant Number
Corresponding Author	Keith R Laws, PhD (CANTAB), Professor, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, Hertfordshire AL10 9AB, United Kingdom. k.laws@herts.ac.uk
Key Words	Dementia; Gender; Sex differences; Cognition
Core Tip	This review assesses evidence that women with Alzheimer’s disease (AD) show greater cognitive impairment than men. The evidence shows that female AD patients are outperformed by males in multiple cognitive domains including visuospatial, verbal processing, semantic and episodic memory. This disadvantage is not attributable to sex differences in age, education level, or dementia severity. Possible explanations include estrogen loss in women or a greater cognitive reserve in men, which may provide protection against the disease process. Such findings have implications for tailoring more specific gender-based treatments.
Publish Date	2016-03-16 12:23
Citation	Laws KR, Irvine K, Gale TM. Sex differences in cognitive impairment in Alzheimer’s disease. World J Psychiatr 2016; 6(1): 54-65
URL	http://www.wjgnet.com/2220-3206/full/v6/i1/54.htm
DOI	http://dx.doi.org/10.5498/wjp.v6.i1.54

Full Article (PDF)	WJP-6-54.pdf
Full Article (Word)	WJP-6-54.doc
Manuscript File	22223-Review.docx
Answering Reviewers	22223-Answering reviewers.pdf
Audio Core Tip	22223-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	22223-Conflict-of-interest statement.pdf
Copyright License Agreement	22223-Copyright assignment.pdf
Peer-review Report	22223-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22223-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22223-Scientific misconduct check.pdf
Scientific Editor Work List	22223-Scientific editor work list.pdf