Publication Name	World Journal of Biological Chemistry
Manuscript ID	22228
Country	Germany

Received	2015-08-24 17:08
Peer-Review Started	2015-08-27 19:36
To Make the First Decision	2015-10-27 10:42
Return for Revision	2015-10-28 13:37
Revised	2015-11-25 15:26
Second Decision	2016-01-04 14:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-19 10:09
Articles in Press	2016-01-19 10:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-02-19 18:51
Publish the Manuscript Online	2016-02-25 19:30

ISSN	1949-8454 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Nutrition & Dietetics
Manuscript Type	Review
Article Title	Complexity of vitamin E metabolism
Manuscript Source	Invited Manuscript
All Author List	Lisa Schmölz, Marc Birringer, Stefan Lorkowski and Maria Wallert
Funding Agency and Grant Number	Funding Agency Grant Number Forschung für die Praxis to Birringer M Federal Ministry of Education and Research and the Deutsche Forschungsgemeinschaft to Lorkowski S as an acknowledgement to the national institutions
Corresponding Author	Stefan Lorkowski, PhD, Department of Nutritional Biochemistry and Physiology, Institute of Nutrition, Friedrich Schiller University Jena, Germany and Competence Center for Nutrition and Cardiovascular Health, Halle-Jena-Leipzig, Dornburger Straße 25, 07743 Jena, Germany. stefan.lorkowski@uni-jena.de
Key Words	Vitamin E metabolism; Long-chain metabolites of vitamin E; Vitamin E bioavailability; Vitamin E transport
Core Tip	Several factors influence vitamin E bioavail-ability. Gender, age and genetic constitution cannot be modified but life-style and vitamin E intake can be. Physiological handling of vitamin E involves intestinal absorption, vascular transport, hepatic sorting by in-tracellular binding proteins, and hepatic metabolism. These processes involve kinetics which vary between the different vitamin E forms. The coordinated metabolism of vitamin E is an effective physiological pathway to prevent excessive accumulation of non-α-tocopherol forms. Interactions with other nutrients or pharmaceutics occur. To evaluate vitamin E status, analytical procedures to detect and quantify vitamin E and metabolites are crucial. Current state-of-the-art analytics are presented.
Publish Date	2016-02-25 19:30
Citation	Schmölz L, Birringer M, Lorkowski S, Wallert M. Complexity of vitamin E metabolism. World J Biol Chem 2016; 7(1): 14-43
URL	http://www.wjgnet.com/1949-8454/full/v7/i1/14.htm
DOI	http://dx.doi.org/10.4331/wjbc.v7.i1.14

Full Article (PDF)	WJBC-7-14.pdf
Full Article (Word)	WJBC-7-14.doc
Manuscript File	22228-Review.docx
Answering Reviewers	22228-Answering reviewers.pdf
Audio Core Tip	22228-Audio core tip.wav
Conflict-of-Interest Disclosure Form	22228-Conflict-of-interest statement.pdf
Copyright License Agreement	22228-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22228-Language certificate.pdf
Peer-review Report	22228-Peer-review(s).pdf
Scientific Misconduct Check	22228-Scientific misconduct check.pdf
Scientific Editor Work List	22228-Scientific editor work list.pdf