Publication Name	World Journal of Diabetes
Manuscript ID	22232
Country	Japan

Received	2015-08-21 16:29
Peer-Review Started	2015-08-24 08:30
To Make the First Decision	2015-10-08 16:09
Return for Revision	2015-10-13 16:06
Revised	2015-10-23 16:26
Second Decision	2015-11-17 15:17
Accepted by Journal Editor-in-Chief	2015-11-18 17:44
Accepted by Executive Editor-in-Chief	2015-12-02 14:30
Articles in Press	2015-12-02 14:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-18 08:11
Publish the Manuscript Online	2015-12-21 09:18

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Osteocalcin as a hormone regulating glucose metabolism
Manuscript Source	Invited Manuscript
All Author List	Ippei Kanazawa
Funding Agency and Grant Number
Corresponding Author	Ippei Kanazawa, MD, PhD, Department of Internal Medicine 1, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan. ippei.k@med.shimane-u.ac.jp
Key Words	Osteocalcin; Undercarboxylated osteocalcin; Glucose; Insulin; Adiponectin; Glucagon-like peptide-1; Diabetes mellitus
Core Tip	Osteocalcin, especially undercarboxylated form of osteocalcin, has an endocrine function to regulate glucose metabolism. Osteocalcin directly stimulates insulin secretion in pancreas and indirectly via increasing glucagon-like peptide-1 secretion in small intestine as well as adiponectin secretion in adipose tissue, and enhances insulin sensitivity in muscle. Therefore, osteocalcin may be an important factor linking between bone and glucose homeostasis.
Publish Date	2015-12-21 09:18
Citation	Kanazawa I. Osteocalcin as a hormone regulating glucose metabolism. World J Diabetes 2015; 6(18): 1345-1354
URL	http://www.wjgnet.com/1948-9358/full/v6/i18/1345.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i18.1345

Full Article (PDF)	WJD-6-1345.pdf
Full Article (Word)	WJD-6-1345.doc
Manuscript File	22232-Review.docx
Answering Reviewers	22232-Answering reviewers.pdf
Audio Core Tip	22232-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22232-Conflict-of-interest statement.pdf
Copyright License Agreement	22232-Copyright assignment.pdf
Peer-review Report	22232-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22232-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22232-Scientific misconduct check.pdf
Scientific Editor Work List	22232-Scientific editor work list.pdf