Publication Name	World Journal of Gastroenterology
Manuscript ID	2224
Country	China

Received	2013-02-07 20:43
Peer-Review Started	2013-02-09 15:42
To Make the First Decision	2013-03-04 10:41
Return for Revision	2013-03-04 14:53
Revised	2013-03-30 11:23
Second Decision	2013-04-09 20:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-10 07:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-05-03 16:22
Typeset the Manuscript	2013-06-05 08:47
Publish the Manuscript Online	2013-06-28 23:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Mitochondrial ATP 6 and 8 polymorphisms in irritable bowel syndrome with diarrhea
Manuscript Source	Invited Manuscript
All Author List	Wei-Feng Wang, Xin Li, Ming-Zhou Guo, Jian-De Chen, Yun-Sheng Yang, Li-Hua Peng, Yong-Hua Wang, Chun-Yan Zhang and Hui-Hui Li
Funding Agency and Grant Number
Corresponding Author	Yun-Sheng Yang, MD, Director, Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China. sunny888@medmail.com.cn
Key Words	Irritable bowel syndrome; Diarrhea; Mitochondrial ATP 6 gene; Mitochondrial ATP 8 gene; Polymorphism
Core Tip	Mitochondrial DNA, the only source of extranuclear genome, was assessed by Camilleri's group in a study of patients with functional gastrointestinal disorders in 2009 which was the first study exploring the possible role of mitochondrial DNA in irritable bowel syndrome (IBS). Up till now, few research efforts have focused on this topic and there is little knowledge about it. Present study revealed that mitochondrial ATP 6 and 8 genes were more frequently mutated in IBS with diarrhea than in healthy individuals. We believe this preliminary finding could help promote future research on mitochondrial DNA in IBS.
Publish Date	2013-06-28 23:55
Citation	Wang WF, Li X, Guo MZ, Chen JD, Yang YS, Peng LH, Wang YH, Zhang CY, Li HH. Mitochondrial ATP 6 and 8 polymorphisms in irritable bowel syndrome with diarrhea. World J Gastroenterol 2013; 19(24): 3847-3853
URL	http://www.wjgnet.com/1007-9327/full/v19/i24/3847.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i24.3847

Full Article (PDF)	WJG-19-3847.pdf
Manuscript File	2224-Review.doc
Answering Reviewers	2224-Answering reviewers.doc
Biostatistics Review Certificate	Signature.pdf
Copyright License Agreement	2224-Copyright assignment.doc
Institutional Review Board Approval Form or Document	科研伦理审批表2013-2.pdf
Non-Native Speakers of English Editing Certificate	2224-Language certificate.pdf
Peer-review Report	2224-Peer review(s).pdf
Scientific Editor Work List	2224-Scientific editor work list.doc