Publication Name	World Journal of Stem Cells
Manuscript ID	22240
Country	Italy

Received	2015-08-22 17:23
Peer-Review Started	2015-08-24 11:41
To Make the First Decision	2015-10-08 16:09
Return for Revision	2015-10-13 16:22
Revised	2015-10-27 18:04
Second Decision	2015-12-10 18:05
Accepted by Journal Editor-in-Chief	2015-12-13 00:16
Accepted by Company Editor-in-Chief	2015-12-21 11:15
Articles in Press	2015-12-21 11:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-12 09:00
Publish the Manuscript Online	2016-01-19 13:45

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Research & Experimental Medicine
Manuscript Type	Review
Article Title	Use of bone morphogenetic proteins in mesenchymal stem cell stimulation of cartilage and bone repair
Manuscript Source	Invited Manuscript
All Author List	Sonia Scarfì
Funding Agency and Grant Number
Corresponding Author	Sonia Scarfì, PhD, Associate Professor of Molecular Biology, Department of Earth, Environment and Life Sciences, University of Genova, Via Pastore 3, 16132 Genova, Italy. soniascarfi@unige.it
Key Words	Mesenchymal stem cells; Cartilage; Bone repair; Bone morphogenetic protein
Core Tip	Since their first identification, bone morphogenetic proteins (BMPs) have attracted the attention for their potential therapeutic use in tissue engineering and biomedical regenerative therapies. In particular, BMP2 and BMP7 have been successfully used in the treatment of a number of cartilage and bone defects, although these strategies present a certain number of concerning side effects. Also in the field of mesenchymal stem cell (MSC) biology there is a continually growing interest, especially in the regulation of their differentiation, and in demonstrating their utility in tissue engineering. The review focuses on the current knowledge of BMP physiological roles in MSC biology and differentiation capacities. In particular it highlights the potentialities of the concomitant clinical use of BMPs and MSCs in cartilage and bone tissue repair.
Publish Date	2016-01-19 13:45
Citation	Scarfì S. Use of bone morphogenetic proteins in mesenchymal stem cell stimulation of cartilage and bone repair. World J Stem Cells 2016; 8(1): 1-12
URL	http://www.wjgnet.com/1948-0210/full/v8/i1/1.htm
DOI	http://dx.doi.org/10.4252/wjsc.v8.i1.1

Full Article (PDF)	WJSC-8-1.pdf
Full Article (Word)	WJSC-8-1.doc
Manuscript File	22240-Review.docx
Answering Reviewers	22240-Answering reviewers.pdf
Audio Core Tip	22240-Audio core tip.wav
Conflict-of-Interest Disclosure Form	22240-Conflict-of-interest statement.pdf
Copyright License Agreement	22240-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22240-Language certificate.pdf
Peer-review Report	22240-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22240-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22240-Scientific misconduct check.pdf
Scientific Editor Work List	22240-Scientific editor work list.pdf