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Articles Published Processes
1/19/2016 1:44:00 PM | Browse: 1216 | Download: 1746
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Received |
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2015-08-22 17:23 |
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Peer-Review Started |
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2015-08-24 11:41 |
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To Make the First Decision |
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2015-10-08 16:09 |
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Return for Revision |
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2015-10-13 16:22 |
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Revised |
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2015-10-27 18:04 |
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Second Decision |
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2015-12-10 18:05 |
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Accepted by Journal Editor-in-Chief |
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2015-12-13 00:16 |
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Accepted by Executive Editor-in-Chief |
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2015-12-21 11:15 |
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Articles in Press |
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2015-12-21 11:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-01-12 09:00 |
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Publish the Manuscript Online |
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2016-01-19 13:45 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Research & Experimental Medicine |
Manuscript Type |
Review |
Article Title |
Use of bone morphogenetic proteins in mesenchymal stem cell stimulation of cartilage and bone repair
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Manuscript Source |
Invited Manuscript |
All Author List |
Sonia Scarfì |
Funding Agency and Grant Number |
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Corresponding Author |
Sonia Scarfì, PhD, Associate Professor of Molecular Biology, Department of Earth, Environment and Life Sciences, University of Genova, Via Pastore 3, 16132 Genova, Italy. soniascarfi@unige.it |
Key Words |
Mesenchymal stem cells; Cartilage; Bone repair; Bone morphogenetic protein |
Core Tip |
Since their first identification, bone morphogenetic proteins (BMPs) have attracted the attention for their potential therapeutic use in tissue engineering and biomedical regenerative therapies. In particular, BMP2 and BMP7 have been successfully used in the treatment of a number of cartilage and bone defects, although these strategies present a certain number of concerning side effects. Also in the field of mesenchymal stem cell (MSC) biology there is a continually growing interest, especially in the regulation of their differentiation, and in demonstrating their utility in tissue engineering. The review focuses on the current knowledge of BMP physiological roles in MSC biology and differentiation capacities. In particular it highlights the potentialities of the concomitant clinical use of BMPs and MSCs in cartilage and bone tissue repair. |
Publish Date |
2016-01-19 13:45 |
Citation |
Scarfì S. Use of bone morphogenetic proteins in mesenchymal stem cell stimulation of cartilage and bone repair. World J Stem Cells 2016; 8(1): 1-12 |
URL |
http://www.wjgnet.com/1948-0210/full/v8/i1/1.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v8.i1.1 |
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