Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	22246
Country	South Korea

Received	2015-08-22 17:41
Peer-Review Started	2015-08-26 09:57
To Make the First Decision	2015-10-21 15:20
Return for Revision	2015-10-30 15:06
Revised	2015-11-04 21:34
Second Decision	2015-12-10 18:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-21 11:16
Articles in Press	2015-12-21 11:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-02 10:01
Publish the Manuscript Online	2016-03-04 12:13

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Efforts to increase image quality during endoscopy: The role of pronase
Manuscript Source	Invited Manuscript
All Author List	Gwang Ha Kim, Yu Kyung Cho, Jae Myung Cha, Sun-Young Lee and Il-Kwun Chung
Funding Agency and Grant Number
Corresponding Author	Il-Kwun Chung, MD, PhD, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, 23-20 Bongmyung-dong, Dongnam-gu, Cheonan 330-721, South Korea. euschung@schmc.ac.kr
Key Words	Endoscopy; Premedication; Pronase
Core Tip	The present review discusses the role of pronase in increasing image quality during endoscopy. Premedication with pronase 10 to 20 min before endo-scopy significantly improves mucosal visibility with-out affecting the accuracy of Helicobacter pylori identi-fication. The effects of pronase as premedication are also applicable in advanced endoscopic procedures such as narrow-band imaging, magnifying endoscopy, or endoscopic ultrasonography. Although improved mucosal visibility does not necessarily improve clinical outcomes, premedication with pronase may be helpful for increasing the detection rate of early cancers.
Publish Date	2016-03-04 12:13
Citation	Kim GH, Cho YK, Cha JM, Lee SY, Chung IK. Efforts to incre­ase image quality during endoscopy: The role of pronase. World J Gastrointest Endosc 2016; 8(5): 267-272
URL	http://www.wjgnet.com/1948-5190/full/v8/i5/267.htm
DOI	http://dx.doi.org/10.4253/wjge.v8.i5.267

Full Article (PDF)	WJGE-8-267.pdf
Full Article (Word)	WJGE-8-267.doc
Manuscript File	22246-Review.docx
Answering Reviewers	22246-Answering reviewers.pdf
Audio Core Tip	22246-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22246-Conflict-of-interest statement.pdf
Copyright License Agreement	22246-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22246-Language certificate.pdf
Peer-review Report	22246-Peer-review(s).pdf
Scientific Misconduct Check	22246-Scientific misconduct check.pdf
Scientific Editor Work List	22246-Scientific editor work list.pdf