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4/11/2016 10:17:00 AM | Browse: 1270 | Download: 1362
Publication Name World Journal of Translational Medicine
Manuscript ID 22290
Country/Territory China
Received
2015-08-27 09:37
Peer-Review Started
2015-08-30 16:11
To Make the First Decision
2015-11-24 14:53
Return for Revision
2015-11-30 14:32
Revised
2015-12-09 20:54
Second Decision
2015-12-28 14:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-01-11 15:46
Articles in Press
2016-01-11 15:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-31 12:22
Publish the Manuscript Online
2016-04-11 10:17
ISSN 2220-6132 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Sphingolipid metabolism affects the anticancer effect of cisplatin
Manuscript Source Invited Manuscript
All Author List Yu-Lan Li, Ming-Lin Lin, Song-Qing He and Jun-Fei Jin
Funding Agency and Grant Number
Corresponding Author Jun-Fei Jin, PhD, Professor, Labora­tory of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, 15 Lequn Road, Guilin 541001, Guangxi Zhuang Autonomous Region, China. changliangzijin@163.com
Key Words Apoptosis; Sphingolipid metabolism; Drug resistance; Cisplatin; Anticancer
Core Tip Cisplatin classifies as a classical anticancer drug and DNA is identified as the most important target of cisplatin. However, increasing evidences have testified that sphingolipid metabolism is associated with the anticancer effect of cisplatin. In this mini-review, we discussed sphingolipid signaling molecules and/or related enzymes affected the anticancer effect of cisplatin, particularly in cisplatin-induced cancer cell apoptosis and drug resistance. Targeting these sphingolipid molecules and enzymes might contribute to the development of novel anticancer strategies or to increase the sensitivity of currently used drugs.
Publish Date 2016-04-11 10:17
Citation Li YL, Lin ML, He SQ, Jin JF. Sphingolipid metabolism affects the anticancer effect of cisplatin. World J Transl Med 2016; 5(1): 37-45
URL http://www.wjgnet.com/2220-6132/full/v5/i1/37.htm
DOI http://dx.doi.org/10.5528/wjtm.v5.i1.37
Full Article (PDF) WJTM-5-37.pdf
Full Article (Word) WJTM-5-37.doc
Manuscript File 22290-Review.doc
Answering Reviewers 22290-Answering reviewers.pdf
Audio Core Tip 22290-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 22290-Conflict-of-interest statement.pdf
Copyright License Agreement 22290-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 22290-Language certificate.pdf
Peer-review Report 22290-Peer-review(s).pdf
Scientific Misconduct Check 22290-Scientific misconduct check.pdf
Scientific Editor Work List 22290-Scientific editor work list.pdf