Publication Name	World Journal of Gastroenterology
Manuscript ID	22321
Country	China

Received	2015-08-26 08:56
Peer-Review Started	2015-08-26 09:26
To Make the First Decision	2015-09-29 17:03
Return for Revision	2015-10-05 14:58
Revised	2015-10-17 20:58
Second Decision	2015-11-27 08:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-08 17:14
Articles in Press	2015-12-08 17:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-11 14:36
Publish the Manuscript Online	2015-12-24 11:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	High antibiotic resistance rate: A difficult issue for Helicobacter pylori eradication treatment
Manuscript Source	Invited Manuscript
All Author List	Mei Zhang
Funding Agency and Grant Number
Corresponding Author	Mei Zhang, MD, Chief Physician, Professor, Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Xuanwu District, Beijing 100053, China. zhang2955@sina.com
Key Words	Helicobacter pylori; Resistance; Eradication treatment; Triple antibiotic therapy; Gastrointestinal disease
Core Tip	Helicobacter pylori (H. pylori) infection is associated with a variety of upper gastrointestinal diseases, including gastric cancer. H. pylori eradication treatment failure affects the outcome of these diseases. The eradication rate of triple antibiotic therapy, the worldwide gold standard, is currently less than 80% in most parts of the world. Antibiotic resistance is the main reason for treatment failure, therefore the standard triple regimen is no longer suitable as a first-line treatment for the majority of the world. H. pylori eradication treatment may fail for a number of reasons, including H. pylori strain factors, host factors, environmental factors, and inappropriate treatment.
Publish Date	2015-12-24 11:11
Citation	Zhang M. High antibiotic resistance rate: A difficult issue for Helicobacter pylori eradication treatment. World J Gastroenterol 2015; 21(48): 13432-13437
URL	http://www.wjgnet.com/1007-9327/full/v21/i48/13432.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i48.13432

Full Article (PDF)	WJG-21-13432.pdf
Full Article (Word)	WJG-21-13432.doc
Manuscript File	22321-Review.docx
Answering Reviewers	22321-Answering reviewers.pdf
Audio Core Tip	22321-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22321-Conflict-of-interest statement.pdf
Copyright License Agreement	22321-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22321-Language certificate.pdf
Peer-review Report	22321-Peer-review(s).pdf
Scientific Misconduct Check	22321-Scientific misconduct check.pdf
Scientific Editor Work List	22321-Scientific editor work list.pdf