Publication Name	World Journal of Nephrology
Manuscript ID	2239
Country

Received	2013-02-17 13:57
Peer-Review Started	2013-02-18 08:51
First Decision by Editorial Office Director
Return for Revision	2013-03-18 09:36
Revised	2013-03-25 23:09
Publication Fee Transferred
Second Decision by Editor	2013-04-10 16:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-04-11 05:13
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-05-15 17:18
Publish the Manuscript Online	2013-06-06 10:41

ISSN	2220-6124 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Editorial
Article Title	Uric acid and chronic kidney disease: A time to act?
Manuscript Source
All Author List	Gianni Bellomo
Funding Agency and Grant Number
Corresponding Author	Gianni Bellomo, MD, Department of Nephrology, San Giovanni Battista Hospital, Via Arcamone 1, 06034 Foligno, Italy. assidial@tin.it
Key Words	Uric acid; Urate; Chronic kidney disease; Allopurinol; Febuxostat; Diabetes; Renal transplantation
Core Tip	The evidence presented so far, derived from experimental, epidemiological, and a few, small, intervention studies, points towards a role for uric acid in the progression of chronic kidney disease and deterioration of renal function. However, conclusive proof, such as that coming from a randomized clinical trial, is lacking. Finally we will briefly discuss the challenges of a trial of uric-acid-lowering treatment, and the recent suggestions on how to conduct such a trial.
Publish Date	2013-06-06 10:41
Citation	Bellomo G. Uric acid and chronic kidney disease: A time to act? World J Nephrol 2013; 2(2): 7-25
URL	http://www.wjgnet.com/2220-6124/full/v2/i2/17.htm
DOI	http://dx.doi.org/10.5527/wjn.v2.i2.17

Full Article (PDF)	WJN-2-17.pdf
Manuscript File	2239-Review.doc
Answering Reviewers	2239-Answering reviewers.pdf
Copyright License Agreement	2239-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2239-Language certificate.pdf
Peer-review Report	2239-Peer review.pdf
Scientific Editor Work List	2239-Scientific editor work list.doc