1/21/2016 4:10:00 PM | Browse: 1173 | Download: 2167
| Publication Name | World Journal of Gastroenterology |
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| Manuscript ID | 22434 |
| Country | Italy |
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| ISSN | 1007-9327 (print) and 2219-2840 (online) |
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| Open Access | Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright | © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Gastroenterology & Hepatology |
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| Manuscript Type | Observational Study |
| Article Title | Italian survey on non-steroidal anti-inflammatory drugs and gastrointestinal bleeding in children |
| Manuscript Source | Unsolicited Manuscript |
| All Author List | Sabrina Cardile, Massimo Martinelli, Arrigo Barabino, Paolo Gandullia, Salvatore Oliva, Giovanni Di Nardo, Luigi Dall'Oglio, Francesca Rea, Gian Luigi de' Angelis, Barbara Bizzarri, Graziella Guariso, Enzo Masci, Annamaria Staiano, Erasmo Miele and Claudio Romano |
| Funding Agency and Grant Number | |
| Corresponding Author | Claudio Romano, MD, Gastroenterology and Endoscopic Unit, Department of Pediatrics, University of Messina, Via Consolare Valeria, 98100 Messina, Italy. romanoc@unime.it |
| Key Words | Hematemesis; Gastrointestinal bleeding; non-steroidal anti-inflammatory drug; Melena; Pediatrics |
| Core Tip | It is known that non-steroidal anti-inflammatory drug (NSAIDs) are one of the most extensively used medications. Adverse effects associated with their use are commonly reported in the gastrointestinal tract. Data on children are limited and evidence is based mainly on case reports, and relatively small cohort studies. Our manuscript represents the first Italian survey focusing on gastrointestinal bleeding occurrences following NSAIDs consumption in a pediatric population. A high number of self-prescriptions and inappropriate use represent the most alarming data. Our data show that the risk of adverse events seems to be related to improper use rather than to NSAIDs safety profile. |
| Publish Date | 2016-01-21 16:10 |
| Citation | Cardile S, Martinelli M, Barabino A, Gandullia P, Oliva S, Di Nardo G, Dall’Oglio L, Rea F, de’ Angelis GL, Bizzarri B, Guariso G, Masci E, Staiano A, Miele E, Romano C. Italian survey on non-steroidal anti-inflammatory drugs and gastrointestinal bleeding in children. World J Gastroenterol 2016; 22(5): 1877-1883 |
| URL | http://www.wjgnet.com/1007-9327/full/v22/i5/1877.htm |
| DOI | http://dx.doi.org/10.3748/wjg.v22.i5.1877 |
| Full Article (PDF) | WJG-22-1877.pdf |
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| Full Article (Word) | WJG-22-1877.doc |
| Manuscript File | 22434-Review.doc |
| Answering Reviewers | 22434-Answering reviewers.pdf |
| Audio Core Tip | 22434-Audio core tip.m4a |
| Biostatistics Review Certificate | 22434-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | Conflict-of-Interest_Statement_20150902223942.pdf |
| Copyright License Agreement | 22434-Copyright assignment.pdf |
| Signed Informed Consent Form(s) or Document(s) | Informed_Consent_Statement_20150902215805.docx |
| Institutional Review Board Approval Form or Document | 22434-Institutional review board statement.pdf |
| Non-Native Speakers of English Editing Certificate | 22434-Language certificate.pdf |
| Peer-review Report | 22434-Peer-review(s).pdf |
| Scientific Misconduct Check | 22434-Scientific misconduct check.pdf |
| Scientific Editor Work List | 22434-Scientific editor work list.pdf |