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3/16/2016 12:22:00 PM | Browse: 1176 | Download: 1373
Publication Name World Journal of Psychiatry
Manuscript ID 22436
Country/Territory Spain
Received
2015-08-29 17:13
Peer-Review Started
2015-09-04 13:28
To Make the First Decision
2015-09-28 12:09
Return for Revision
2015-10-10 10:54
Revised
2015-11-08 19:31
Second Decision
2016-01-18 19:43
Accepted by Journal Editor-in-Chief
2016-01-18 22:28
Accepted by Company Editor-in-Chief
2016-01-22 16:25
Articles in Press
2016-01-22 16:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-03 17:39
Publish the Manuscript Online
2016-03-16 12:23
ISSN 2220-3206 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Review
Article Title Are the changes in the peripheral brain-derived neurotrophic factor levels due to platelet activation?
Manuscript Source Invited Manuscript
All Author List Montserrat Serra-Millàs
Funding Agency and Grant Number
Corresponding Author Montserrat Serra-Millàs, PhD, Osona Mental Health, Hospital Universitari de Vic, Salut Mental i Innovació Social (SaMIS), Universitat de Vic-Universitat Central de Catalunya, C/Francesc Pla «El Vigatà» nº 1, 08500 Vic, Barcelona, Spain. serra2mont@yahoo.es
Key Words Platelets; Brain derived neurotrophic factor; Depression; Antidepressants; Biomarkers
Core Tip Brain-derived neurotrophic factor (BDNF) is expressed in neuronal and non- neuronal tissues and is stored peripherally in platelets. Platelet BDNF is present in α-granules and cytoplasm and only BDNF of granules is released by agonist stimulation. Little is known about mechanisms related to BDNF release in human platelets. Depressive disorders are associated with BDNF and platelet dysfunction. Low levels of serum BDNF have been described in major depression and they increased with antidepressant treatment. Only a few studies have evaluated the relationship between platelet activation and peripheral BDNF values. This review suggests that platelet reactivity may partly explain the alterations in BDNF.
Publish Date 2016-03-16 12:23
Citation Serra-Millàs M. Are the changes in the peripheral brain-derived neurotrophic factor levels due to platelet activation? World J Psychiatr 2016; 6(1): 84-101
URL http://www.wjgnet.com/2220-3206/full/v6/i1/84.htm
DOI http://dx.doi.org/10.5498/wjp.v6.i1.84
Full Article (PDF) WJP-6-84.pdf
Full Article (Word) WJP-6-84.doc
Manuscript File 22436-Review.doc
Answering Reviewers 22436-Answering reviewers.pdf
Audio Core Tip 22436-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 22436-Conflict-of-interest statement.pdf
Copyright License Agreement 22436-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 22436-Language certificate.pdf
Peer-review Report 22436-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 22436-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 22436-Scientific misconduct check.pdf
Scientific Editor Work List 22436-Scientific editor work list.pdf