Publication Name	World Journal of Virology
Manuscript ID	22470
Country	United States

Received	2015-08-29 16:03
Peer-Review Started	2015-09-07 08:38
To Make the First Decision	2015-10-08 16:18
Return for Revision	2015-10-19 00:22
Revised	2015-10-28 09:01
Second Decision	2015-11-30 12:28
Accepted by Journal Editor-in-Chief	2015-12-02 06:18
Accepted by Executive Editor-in-Chief	2015-12-08 15:43
Articles in Press	2015-12-08 15:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-26 21:58
Publish the Manuscript Online	2016-02-01 13:23

ISSN	2220-3249 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Virology
Manuscript Type	Review
Article Title	Infected cell protein 0 functional domains and their coordination in herpes simplex virus replication
Manuscript Source	Invited Manuscript
All Author List	Haidong Gu
Funding Agency and Grant Number	Funding Agency Grant Number National Institute of Allergy and Infectious Diseases 1R01AI118992
Corresponding Author	Haidong Gu, PhD, Assistant Professor, Department of Biological Sciences, Wayne State University, 5047 Gullen Mall, Detroit, MI 48202, United States. haidong.gu@wayne.edu
Key Words	Subcellular translocation; Herpes simplex virus 1; Infected cell protein 0; E3 ubiquitin ligase; Protein modification; ND10 nuclear bodies; Chromatin repression
Core Tip	Due to the genomic limitation, viruses often use multifunctional proteins to ensure viral replication. Coordination of the multiple viral functions is critical for a successful viral infection. Infected cell protein 0 (ICP0) is notoriously multi-functional in terms of simultaneously targeting many host machineries located in different cellular compartments. Understanding the molecular basis of ICP0 multifunctionality is important for not only the elucidation of herpes simplex virus pathogenicity but also the delineation of host defense mechanisms.
Publish Date	2016-02-01 13:23
Citation	Gu H. Infected cell protein 0 functional domains and their coordination in herpes simplex virus replication. World J Virol 2016; 5(1): 1-13
URL	http://www.wjgnet.com/2220-3249/full/v5/i1/1.htm
DOI	http://dx.doi.org/10.5501/wjv.v5.i1.1

Full Article (PDF)	WJV-5-1.pdf
Full Article (Word)	WJV-5-1.doc
Manuscript File	22470-Review.doc
Answering Reviewers	22470-Answering reviewers.pdf
Audio Core Tip	22470-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22470-Conflict-of-interest statement.pdf
Copyright License Agreement	22470-Copyright assignment.pdf
Peer-review Report	22470-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22470-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22470-Scientific misconduct check.pdf
Scientific Editor Work List	22470-Scientific editor work list.pdf