Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	22511
Country	United States

Received	2015-09-05 14:14
Peer-Review Started	2015-09-08 10:39
To Make the First Decision	2015-10-08 16:39
Return for Revision	2015-10-16 18:04
Revised	2015-10-21 09:50
Second Decision	2015-12-12 17:16
Accepted by Journal Editor-in-Chief	2015-12-13 08:33
Accepted by Executive Editor-in-Chief	2015-12-21 11:30
Articles in Press	2015-12-21 11:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-02-26 09:37
Publish the Manuscript Online	2016-03-07 11:32

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Minireviews
Article Title	Emerging role of cystic fibrosis transmembrane conductanceregulator - an epithelial chloride channel in gastrointestinalcancers
Manuscript Source	Invited Manuscript
All Author List	Yuning Hou, Xiaoqing Guan, Zhe Yang and Chunying Li
Funding Agency and Grant Number	Funding Agency Grant Number American Cancer Society Institutional Research 11-053-01-IRG (to Li C) National Institutes of Health HL128647 (to Li C)
Corresponding Author	Chunying Li, PhD, Department of Biochemistry and Molecular Biology, Karmanos Cancer Institute, Wayne State University School of Medicine, 540 E. Canfield Avenue, 5312 Scott Hall, Detroit, MI 48201, United States. cl@med.wayne.edu
Key Words	Gastrointestinal cancer; Protein interaction; Cystic fibrosis transmembrane conductance regulator; Nuclear factor kB; Signaling molecule
Core Tip	The present review aimed to analyze most published data regarding the emerging role of cystic fibrosis transmembrane conductance regulator (CFTR), an epithelial chloride channel in many tissues and organs, in various cancers, with the focus on the link between CFTR dysfunction and gastrointestinal cancers. The possible underlying mechanisms have also been discussed.
Publish Date	2016-03-07 11:32
Citation	Hou Y, Guan X, Yang Z, Li C. Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers. World J Gastrointest Oncol 2016; 8(3): 282-288
URL	http://www.wjgnet. com/1948-5204/full/v8/i3/282.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i3.282

Full Article (PDF)	WJGO-8-282.pdf
Full Article (Word)	WJGO-8-282.doc
Manuscript File	22511-Review.docx
Answering Reviewers	22511-Answering reviewers.pdf
Audio Core Tip	22511-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22511-Conflict-of-interest statement.pdf
Copyright License Agreement	22511-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22511-Language certificate.pdf
Peer-review Report	22511-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22511-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22511-Scientific misconduct check.pdf
Scientific Editor Work List	22511-Scientific editor work list.pdf