Publication Name	World Journal of Gastroenterology
Manuscript ID	22520
Country	China

Received	2015-09-01 09:07
Peer-Review Started	2015-09-01 17:13
To Make the First Decision	2015-10-15 08:35
Return for Revision	2015-10-21 14:29
Revised	2015-11-15 19:07
Second Decision	2015-12-03 08:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-14 16:11
Articles in Press	2015-12-14 16:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-12-23 12:00
Typeset the Manuscript	2016-02-19 10:24
Publish the Manuscript Online	2016-03-04 19:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Cohort Study
Article Title	Ten-year survival of hepatocellular carcinoma patients undergoing radiofrequency ablation as a first-line treatment
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Yang, Kun Yan, S Nahum Goldberg, Muneeb Ahmed, Jung-Chieh Lee, Wei Wu, Zhong-Yi Zhang, Song Wang and Min-Hua Chen
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81471768 Municipal Natural Science Foundation of Beijing of China 7152031 Beijing Municipal Health System Special Funds of High-Level Medical Personnel Construction 2013-3-086
Corresponding Author	Min-Hua Chen, Professor, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Ultrasound, Peking University Cancer Hospital and Institute, 52 Fucheng Road, Haidian District, Beijing 100142, China. minhuachen@vip.sina.com
Key Words	Radiofrequency ablation; Hepatocellular carcinoma; Percutaneous; Ultrasonography-guided; Long term survival
Core Tip	Numerous large series have shown that percutaneous radiofrequency ablation (RFA) is safe and effective, with minimal morbidity and mortality in hepatocellular carcinoma (HCC) treatment. However, few studies had follow-up time that was adequate to rival that of surgery and percutaneous ethanol injection. In our long-term follow-up study on a large group of HCC patients, we further confirmed that RFA could achieve a 10-year survival in HCC patients as a first-line treatment, especially for patients with liver function of Child-Pugh class A, a single tumor, and without portal vein hypertension.
Publish Date	2016-03-04 19:53
Citation	Yang W, Yan K, Goldberg SN, Ahmed M, Lee JC, Wu W, Zhang ZY, Wang S, Chen MH. Ten-year survival of hepatocellular carcinoma patients undergoing radiofrequency ablation as a first-line treatment. World J Gastroenterol 2016; 22(10): 2993-3005
URL	http://www.wjgnet.com/1007-9327/full/v22/i10/2993.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i10.2993

Full Article (PDF)	WJG-22-2993.pdf
Full Article (Word)	WJG-22-2993.doc
Manuscript File	22520-Review.doc
Answering Reviewers	22520-Answering reviewers.pdf
Audio Core Tip	22520-Audio core tip.mp3
Biostatistics Review Certificate	22520-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	22520-Conflict-of-interest statement.pdf
Copyright License Agreement	22520-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150831213316.doc
Institutional Review Board Approval Form or Document	22520-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	22520-Language certificate.pdf
Peer-review Report	22520-Peer-review(s).pdf
Scientific Misconduct Check	22520-Scientific misconduct check.pdf
Scientific Editor Work List	22520-Scientific editor work list.pdf