Publication Name	World Journal of Clinical Oncology
Manuscript ID	22539
Country	United States

Received	2015-09-02 08:39
Peer-Review Started	2015-09-08 09:47
To Make the First Decision	2015-10-08 15:43
Return for Revision	2015-10-16 17:21
Revised	2015-10-19 23:01
Second Decision	2015-12-12 17:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-21 11:31
Articles in Press	2015-12-21 11:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-28 12:03
Publish the Manuscript Online	2016-04-07 11:01

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Case Report
Article Title	Gallbladder adenocarcinoma and paraneoplastic parathyroid hormone mediated hypercalcemia
Manuscript Source	Unsolicited Manuscript
All Author List	Meera Yogarajah, Bhradeev Sivasambu and Zewge Shiferaw-Deribe
Funding Agency and Grant Number
Corresponding Author	Meera Yogarajah, MD, Department of Medicine, Interfaith Medical Center, 1545 Atlantic Avenue, Brooklyn, NY 11213, United States. meera.yogarajah@gmail.com
Key Words	Paraneoplastic hypercalcemia; Gallbladder adenocarcinoma; Hypercalcemia; Hyperparathyroidism; Ectopic parathyroid secretion
Core Tip	Gallbladder carcinoma rarely can cause hyper-calcemia with very few reported cases but they were all due to parathyroid hormone (PTH) related peptide. We present the first case of metastatic gallbladder adenocarcinoma with hypercalcemia due to ectopic PTH secretion from tumor cells. PTH mediated hypercalcemia is not exclusively primary hyperparathyroidism and awareness of this rare paraneoplastic presentation will prevent unnecessary parathyroid surgeries. Moreover this case prompts physicians to look for another ectopic source in the ab-sence of parathyroid lesion which would facilitate early diagnosis of an underlying malignancy.
Publish Date	2016-04-07 11:01
Citation	Yogarajah M, Sivasambu B, Shiferaw-Deribe Z. Gallbladder adenocarcinoma and paraneoplastic parathyroid hormone mediated hypercalcemia. World J Clin Oncol 2016; 7(2): 265-269
URL	http://www.wjgnet.com/2218-4333/full/v7/i2/265.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i2.265

Full Article (PDF)	WJCO-7-265.pdf
Full Article (Word)	WJCO-7-265.doc
Manuscript File	22539-Review.docx
Answering Reviewers	22539-Answering reviewers.pdf
Audio Core Tip	22539-Audio core tip.mp3
Biostatistics Review Certificate	Biostatistics_Statement_20150902011954.docx
Conflict-of-Interest Disclosure Form	22539-Conflict-of-interest statement.pdf
Copyright License Agreement	22539-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150902012016.doc
Institutional Review Board Approval Form or Document	22539-Institutional review board statement.pdf
Peer-review Report	22539-Peer-review(s).pdf
Scientific Misconduct Check	22539-Scientific misconduct check.pdf
Scientific Editor Work List	22539-Scientific editor work list.pdf