Publication Name	World Journal of Cardiology
Manuscript ID	2256
Country	Greece

Received	2013-02-11 15:26
Peer-Review Started	2013-02-13 12:46
To Make the First Decision	2013-03-25 15:19
Return for Revision	2013-03-28 20:34
Revised	2013-05-15 04:14
Second Decision	2013-06-03 16:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-06-04 09:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-11 18:58
Publish the Manuscript Online	2013-08-02 14:08

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Autobiography
Article Title	Ibutilide and novel indexes of ventricular repolarization in persistent atrial fibrillation patients
Manuscript Source	Invited Manuscript
All Author List	Panagiotis Korantzopoulos, Konstantinos P Letsas, Anna Kotsia, Giannis Baltogiannis, Kallirroi Kalantzi, Konstantinos Kyrlas and John A Goudevenos
Funding Agency and Grant Number
Corresponding Author	Panagiotis Korantzopoulos, MD, PhD, Department of Cardiology, University of Ioannina Medical School, Campus, PO Box 1186, 45110 Ioannina, Greece. p.korantzopoulos@yahoo.gr
Key Words	Ibutilide; Ventricular repolarization; Arrhythmic risk; Proarrhythmia; Dispersion of repolarization; T peak-to-end; T peak-to-end/QT ratio
Core Tip	In this pilot study we examined the effect of ibutilide on novel indexes of repolarization in patients with persistent atrial fibrillation scheduled for electrical cardioversion. Electrocardiographic (ECG) indexes such as corrected QT interval, the interval from the peak until the end of T wave (Tpe), and the Tpe/QT ratio were measured. We showed that ibutilide significantly increases the dispersion of ventricular repolarization as assessed by modern ECG markers such as Tpe interval and Tpe/QT ratio. These indexes may have a prognostic value with regard to drug-induced proarrhythmia.
Publish Date	2013-08-02 14:08
Citation	Korantzopoulos P, Letsas KP, Kotsia A, Baltogiannis G, Kalantzi K, Kyrlas K, Goudevenos JA. Ibutilide and novel indexes of ventricular repolarization in persistent atrial fibrillation patients. World J Cardiol 2013; 5(7): 242-246
URL	http://www.wjgnet.com/1949-8462/full/v5/i7/242.htm
DOI	http://dx.doi.org/10.4330/wjc.v5.i7.242

Full Article (PDF)	WJC-5-242.pdf
Manuscript File	2256-Review.docx
Answering Reviewers	2256-Answering reviewers.pdf
Copyright License Agreement	2256-Copyright assignment.pdf
Peer-review Report	2256-Peer reviews.pdf
Scientific Editor Work List	2256-Scientific editor work list.doc