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3/30/2016 3:59:00 PM | Browse: 1565 | Download: 2055
Publication Name World Journal of Hepatology
Manuscript ID 22585
Country United States
Received
2015-09-13 10:44
Peer-Review Started
2015-09-16 16:02
To Make the First Decision
2015-10-28 18:07
Return for Revision
2015-11-07 16:16
Revised
2015-11-18 12:15
Second Decision
2016-02-29 09:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-03-14 11:49
Articles in Press
2016-03-14 11:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-21 16:06
Publish the Manuscript Online
2016-03-30 15:59
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Metabolomics studies identify novel diagnostic and prognostic indicators in patients with alcoholic hepatitis
Manuscript Source Unsolicited Manuscript
All Author List Mona Ascha, Zeneng Wang, Mustafa S Ascha, Raed Dweik, Nizar N Zein, David Grove, J Mark Brown, Stephanie Marshall, Rocio Lopez and Ibrahim A Hanouneh
Funding Agency and Grant Number
Funding Agency Grant Number
NIH R01 HL122283 (In part, to Brown JM)
Corresponding Author Ibrahim A Hanouneh, MD, Minnesota Gastroenterology, P.O. Box 14909, Minneapolis, Minnesota, PA 55414, United States. ibrahim.hanouneh@mngastro.com
Key Words Metabolomics; Biomarkers; Liver disease; Model for end-stage liver disease; Cirrhosis; Alcoholic hepatitis; Liver biopsy
Core Tip The model for end-stage liver disease score, which is commonly used to predict outcomes in patients who have liver disease, is far from perfect. We report results from a study that uses metabolomics biomarkers as a means for assessing diagnosis and prognosis in patients who have liver disease. Plasma analytes from fasted subjects have provided information regarding 3 and 6 mo transplant free survival. This study is one of the first to employ the novel metabolomics approach as it relates to patient outcomes. These results can pave the way for future research that can enhance the way we assess patients with liver disease.
Publish Date 2016-03-30 15:59
Citation Ascha M, Wang Z, Ascha MS, Dweik R, Zein NN, Grove D, Brown JM, Marshall S, Lopez R, Hanouneh IA. Metabolomics studies identify novel diagnostic and prognostic indicators in patients with alcoholic hepatitis. World J Hepatol 2016; 8(10): 499-508
URL http://www.wjgnet.com/1948-5182/full/v8/i10/499.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i10.499
Full Article (PDF) WJH-8-499.pdf
Full Article (Word) WJH-8-499.doc
Manuscript File 22585-Review.docx
Answering Reviewers 22585-Answering reviewers.pdf
Audio Core Tip 22585-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 22585-Conflict-of-interest statement.pdf
Copyright License Agreement 22585-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 22585-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 22585-Institutional review board statement.pdf
Supplementary Material Supplementary_Material_20150912211133.pdf
Peer-review Report 22585-Peer-review(s).pdf
Scientific Misconduct Check 22585-Scientific misconduct check.pdf
Scientific Editor Work List 22585-Scientific editor work list.pdf