Publication Name	World Journal of Dermatology
Manuscript ID	22633
Country	Australia

Received	2015-09-09 17:32
Peer-Review Started	2015-09-10 13:58
To Make the First Decision	2015-10-27 11:06
Return for Revision	2015-11-07 13:55
Revised	2015-11-23 11:52
Second Decision	2016-01-18 10:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-29 17:46
Articles in Press	2016-01-29 17:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-13 11:31
Publish the Manuscript Online	2016-04-25 09:44

ISSN	2218-6190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Dermatology
Manuscript Type	Review
Article Title	P2X7 receptor in skin biology and diseases
Manuscript Source	Invited Manuscript
All Author List	Nicholas J Geraghty, Debbie Watson, Sam R Adhikary and Ronald Sluyter
Funding Agency and Grant Number
Corresponding Author	Ronald Sluyter, PhD, Associate Professor, School of Biological Sciences, University of Wollongong, North­fields Avenue, Wollongong NSW 2522, Australia. rsluyter@uow.edu.au
Key Words	P2X7 receptor; Purinergic receptor; Extracellular adenosine triphosphate; CD39; Skin biology; Skin immune system
Core Tip	The P2X7 receptor is present on immune, stromal and epithelial cells. Activation of this receptor by its natural ligand, extracellular adenosine triphosphate, causes a variety of downstream effects including release of inflammatory mediators and growth factors, as well as cell death. P2X7 has various functions on skin cells, and studies of mouse models of disease and of human cells and tissues highlight emerging roles for this receptor in common skin disorders.
Publish Date	2016-04-25 09:44
Citation	Geraghty NJ, Watson D, Adhikary SR, Sluyter R. P2X7 receptor in skin biology and diseases. World J Dermatol 2016; 5(2): 72-83
URL	http://www.wjgnet.com/2218-6190/full/v5/i2/72.htm
DOI	http://dx.doi.org/10.5314/wjd.v5.i2.72

Full Article (PDF)	WJD-5-72.pdf
Full Article (Word)	WJD-5-72.doc
Manuscript File	22633-Review.docx
Answering Reviewers	22633-Answering reviewers.pdf
Audio Core Tip	22633-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22633-Conflict-of-interest statement.pdf
Copyright License Agreement	22633-Copyright assignment.pdf
Peer-review Report	22633-Peer-review(s).pdf
Scientific Misconduct Check	22633-Scientific misconduct check.pdf
Scientific Editor Work List	22633-Scientific editor work list.pdf