Publication Name	World Journal of Stem Cells
Manuscript ID	22635
Country	Italy

Received	2015-09-10 09:07
Peer-Review Started	2015-09-10 14:43
To Make the First Decision	2015-10-08 15:55
Return for Revision	2015-10-16 14:02
Revised	2015-11-06 23:49
Second Decision	2016-01-25 14:41
Accepted by Journal Editor-in-Chief	2016-01-27 10:32
Accepted by Executive Editor-in-Chief	2016-02-16 09:18
Articles in Press	2016-02-16 09:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-29 11:32
Publish the Manuscript Online	2016-04-13 13:33

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Human induced pluripotent stem cells for monogenic disease modelling and therapy
Manuscript Source	Invited Manuscript
All Author List	Paola Spitalieri, Valentina Rosa Talarico, Michela Murdocca, Giuseppe Novelli and Federica Sangiuolo
Funding Agency and Grant Number	Funding Agency Grant Number Agenzia Spaziale Italiana, CoReA 2013-084-R.0
Corresponding Author	Federica Sangiuolo, PhD, Department of Biomedicine and Prevention, Tor Vergata University, via Montpellier, 1, 00133 Rome, Italy. sangiuolo@med.uniroma2.it
Key Words	Human induced pluripotent stem cells; Gene therapy; Monogenic diseases; Gene editing; Foetal cells; Reprogramming techniques; Differentiation
Core Tip	With the development of human induced pluripotent stem cells (hiPSCs) deriving from patients, we can begin to understand the molecular mechanisms underlying monogenic diseases and consequently identify new drugs for their treatment. hiPSCs can differentiate into many disease-relevant cell types, providing in this way to innovative applications in the field of cell replacement therapy, disease modelling, drug testing and drug discovery.
Publish Date	2016-04-13 13:33
Citation	Spitalieri P, Talarico VR, Murdocca M, Novelli G, Sangiuolo F. Human induced pluripotent stem cells for monogenic disease modelling and therapy. World J Stem Cells 2016; 8(4): 118-135
URL	http://www.wjgnet.com/1948-0210/full/v8/i4/118.htm
DOI	http://dx.doi.org/10.4252/wjsc.v8.i4.118

Full Article (PDF)	WJSC-8-118.pdf
Full Article (Word)	WJSC-8-118.doc
Manuscript File	22635-Review.docx
Answering Reviewers	22635-Answering reviewers.pdf
Audio Core Tip	22635-Audio core tip.wav
Conflict-of-Interest Disclosure Form	22635-Conflict-of-interest statement.pdf
Copyright License Agreement	22635-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	22635-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	22635-Language certificate.pdf
Peer-review Report	22635-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22635-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22635-Scientific misconduct check.pdf
Scientific Editor Work List	22635-Scientific editor work list.pdf