Publication Name	World Journal of Hepatology
Manuscript ID	22652
Country	Italy

Received	2015-09-11 11:01
Peer-Review Started	2015-09-11 11:45
To Make the First Decision	2015-10-27 11:06
Return for Revision	2015-11-07 14:19
Revised	2015-11-26 04:55
Second Decision	2016-03-14 17:57
Accepted by Journal Editor-in-Chief	2016-03-14 23:05
Accepted by Company Editor-in-Chief	2016-03-25 14:13
Articles in Press	2016-03-25 14:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-07 09:21
Publish the Manuscript Online	2016-04-11 12:19

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Hepatic resection beyond barcelona clinic liver cancer indication: When and how
Manuscript Source	Invited Manuscript
All Author List	Mattia Garancini, Enrico Pinotti, Stefano Nespoli, Fabrizio Romano, Luca Gianotti and Vittorio Giardini
Funding Agency and Grant Number
Corresponding Author	Mattia Garancini, MD, Department of Surgery, Hepatobiliopancreatic Unit, San Gerardo Hospital, University of Milano Bicocca, Via Pergolesi 33, 20900 Monza, Italy. mattia_garancini@yahoo.it
Key Words	Hepatocellular carcinoma; Liver surgery; Hepatic resection; Multiple hepatocellular carcinoma; Cirrhosis; Barcelona clinic liver cancer; Multidisciplinary approach; Intraoperative ultrasound; Laparoscopy; Portal hypertension
Core Tip	According to the barcelona clinic liver cancer (BCLC) classification liver resection should be performed only in patients with small single hepatocellular carci-noma of 2-3 cm without signs of portal hypertension (PHT). Nevertheless, many studies have shown that patients with multiple and large hepatocellular carci-noma, as like as those with macrovascular infiltration and PHT, could benefit from liver resection. Conse-quently BCLC algorithm should be updated and revised. The aim of this review was to analyze when and how liver resection could be indicated beyond BCLC indications. In this perspective, the role of multi-disciplinary approach, of intraoperative ultrasound and of laparoscopy have been enhanced.
Publish Date	2016-04-11 12:19
Citation	Garancini M, Pinotti E, Nespoli S, Romano F, Gianotti L, Giardini V. Hepatic resection beyond barcelona clinic liver cancer indication: When and how. World J Hepatol 2016; 8(11): 513-519
URL	http://www.wjgnet.com/1948-5182/full/v8/i11/513.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i11.513

Full Article (PDF)	WJH-8-513.pdf
Full Article (Word)	WJH-8-513.doc
Manuscript File	22652-Review.doc
Answering Reviewers	22652-Answering reviewers.pdf
Audio Core Tip	22652-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22652-Conflict-of-interest statement.pdf
Copyright License Agreement	22652-Copyright assignment.pdf
Peer-review Report	22652-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22652-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22652-Scientific misconduct check.pdf
Scientific Editor Work List	22652-Scientific editor work list.pdf