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Articles Published Processes
11/27/2015 5:17:00 PM | Browse: 1157 | Download: 1986
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Received |
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2015-09-18 17:27 |
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Peer-Review Started |
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2015-09-19 12:52 |
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To Make the First Decision |
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2015-10-21 08:58 |
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Return for Revision |
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2015-10-29 10:50 |
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Revised |
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2015-11-02 14:40 |
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Second Decision |
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2015-11-04 15:46 |
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Accepted by Journal Editor-in-Chief |
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2015-11-05 18:26 |
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Accepted by Executive Editor-in-Chief |
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2015-11-11 18:23 |
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Articles in Press |
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2015-11-11 18:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-11-24 13:38 |
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Publish the Manuscript Online |
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2015-11-27 17:14 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Portal vein thrombosis, mortality and hepatic decompensation in patients with cirrhosis: A meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jonathan G Stine, Puja M Shah, Scott L Cornella, Sean R Rudnick, Marwan S Ghabril, George J Stukenborg and Patrick G Northup |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Institutes of Health (In part) |
5T32DK007769-15 |
| NIH-Surgical Oncology |
T32 CA163177 |
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| Corresponding Author |
Jonathan G Stine, MD, MSc, Division of Gastroenterology and Hepatology, University of Virginia, JPA and Lee Street, MSB 2145, PO Box 800708, Charlottesville, VA 22908, United States. jgs9f@virginia.edu
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| Key Words |
Hepatology; Coagulopathy; Liver; Ascites; Hepatic encephalopathy; Portal hypertension |
| Core Tip |
Portal vein thrombosis (PVT) is a common complication of cirrhosis with resultant downstream hepatic decompensation and mortality. Treatment options carry risk and are not without complications. To date, there is a lack of systematic evidence on the clinical importance of PVT. We performed a systematic review and meta-analysis to determine the aggregate estimates of effect of PVT on hepatic decompensation and mortality. PVT appears to significantly increase mortality (OR = 1.62, 95%CI: 1.11-2.36) and ascites (OR = 2.52, 95%CI: 1.63-3.89), however, the small number of included studies limits more generalizable conclusions. More trials with a direct comparison group are needed.
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| Publish Date |
2015-11-27 17:14 |
| Citation |
Stine JG, Shah PM, Cornella SL, Rudnick SR, Ghabril MS, Stukenborg GJ, Northup PG. Portal vein thrombosis, mortality and hepatic decompensation in patients with cirrhosis: A meta-analysis. World J Hepatol 2015; 7(27): 2774-2780 |
| URL |
http://www.wjgnet.com/1948-5182/full/v7/i27/2774.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v7.i27.2774 |
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