Publication Name	World Journal of Gastroenterology
Manuscript ID	2276
Country	New Zealand

Received	2013-02-15 16:49
Peer-Review Started	2013-02-16 10:17
To Make the First Decision	2013-03-11 14:53
Return for Revision	2013-03-18 11:04
Revised	2013-04-05 05:38
Second Decision	2013-04-15 16:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-16 08:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-09 13:51
Publish the Manuscript Online	2013-11-08 14:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Autobiography
Article Title	Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	James D Falvey, Robert W Bentley, Tony R Merriman, Mark B Hampton, Murray L Barclay, Richard B Gearry and Rebecca L Roberts
Funding Agency and Grant Number	Funding Agency Grant Number Health Research Council of New Zealand Scholarships from the Canterbury Gastroenterology Research Trust New Zealand Society of Gastroenterology Ferring Scholarship Bowel and Liver Trust Canterbury to Falvey JD University of Otago to Falvey JD
Corresponding Author	Dr. Rebecca L Roberts, Department of Surgical Sciences, Dunedin School of Medicine, 310 Great King St, PO Box 913, Dunedin 9054, New Zealand. rebecca.roberts@otago.ac.nz
Key Words	Crohn's disease; Ulcerative colitis; Migration inhibitory factor; rs755622; rs5844572; Genetic association study
Core Tip	Migration inhibitory factor (MIF) is an important mediator of inflammatory bowel disease (IBD). However, whether promoter polymorphisms in MIF alter susceptibility to IBD is unclear. This study sought to clarify this, as definitively as possible, for Caucasians and East Asians. Analysis of a New Zealand Caucasian cohort found no association of the polymorphisms MIF -173G > C and CATT5-8 with IBD. Subsequent meta-analysis of the New Zealand data with published MIF -173G > C data from other Caucasian cohorts found no association. A separate meta-analysis of East Asian datasets also found no evidence of association of this promoter polymorphism with IBD.
Publish Date	2013-11-08 14:06
Citation	Falvey JD, Bentley RW, Merriman TR, Hampton MB, Barclay ML, Gearry RB, Roberts RL. Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis. World J Gastroenterol 2013; 19(39): 6656-6664
URL	http://www.wjgnet.com/1007-9327/full/v19/i39/6656.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i39.6656

Full Article (PDF)	WJG-19-6656.pdf
Manuscript File	2276-Review.doc
Answering Reviewers	2276-Answering reviewers.pdf
Copyright License Agreement	2276-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Reapproval_2011.doc
Peer-review Report	2276-Peer reviews.pdf
Scientific Editor Work List	2276-Scientific editor work list.doc