Publication Name	World Journal of Nephrology
Manuscript ID	22809
Country	France

Received	2015-09-25 08:22
Peer-Review Started	2015-10-06 00:34
To Make the First Decision	2015-12-04 11:21
Return for Revision	2015-12-07 16:49
Revised	2015-12-30 19:11
Second Decision	2016-01-22 15:08
Accepted by Journal Editor-in-Chief	2016-01-23 13:16
Accepted by Executive Editor-in-Chief	2016-01-29 18:04
Articles in Press	2016-01-29 18:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-02-18 09:43
Publish the Manuscript Online	2016-03-01 14:46

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	How botulinum toxin in neurogenic detrusor overactivity can reduce upper urinary tract damage?
Manuscript Source	Invited Manuscript
All Author List	Maximilien Baron, Philippe Grise and Jean-Nicolas Cornu
Funding Agency and Grant Number
Corresponding Author	Jean-Nicolas Cornu, MD, PhD, Depart¬ment of Urology, Rouen University Hospital, 1 Rue de Germont, 76031 Rouen Cedex 1, France. jeannicolas.cornu@gmail.com
Key Words	Botulinum toxin; Urinary tract infection; Kidney function; Neurogenic detrusor overactivity; Hydronephrosis; Urolithiasis
Core Tip	Intradetrusor injection of botulinum toxin prevent damage of the upper urinary tract via several potential mechanisms including reduction of bladder pressure, urothelium and suburothelium modifications, sensory receptors expression, and hypoxia reduction. These data could explain the favourable effects of intradetrusor injection of botulinum toxin on urinary tract infections, stone disease, vesico ureteral reflux, hydronephrosis, renal function.
Publish Date	2016-03-01 14:46
Citation	Baron M, Grise P, Cornu JN. How botulinum toxin in neurogenic detrusor overactivity can reduce upper urinary tract damage? World J Nephrol 2016; 5(2): 195-203
URL	http://www.wjgnet.com/2220-6124/full/v5/i2/195.htm
DOI	http://dx.doi.org/10.5527/wjn.v5.i2.195

Full Article (PDF)	WJN-5-195.pdf
Full Article (Word)	WJN-5-195.doc
Manuscript File	22809-Review.doc
Answering Reviewers	22809-Answering reviewers.pdf
Audio Core Tip	22809-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	22809-Conflict-of-interest statement.pdf
Copyright License Agreement	22809-Copyright assignment.pdf
Peer-review Report	22809-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22809-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22809-Scientific misconduct check.pdf
Scientific Editor Work List	22809-Scientific editor work list.pdf