Publication Name	World Journal of Hepatology
Manuscript ID	22814
Country	United States

Received	2015-09-25 14:31
Peer-Review Started
To Make the First Decision
Return for Revision
Revised
Second Decision	2015-09-28 08:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-28 08:25
Articles in Press	2015-09-28 08:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-08 17:21
Publish the Manuscript Online	2015-10-30 11:57

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Recent advances in vaccination of non-responders to standard dose hepatitis B virus vaccine
Manuscript Source	Invited Manuscript
All Author List	Saqib Walayat, Zohair Ahmed, Daniel Martin, Srinivas Puli, Michael Cashman and Sonu Dhillon
Funding Agency and Grant Number
Corresponding Author	Sonu Dhillon, MD, Department of Gastroenterology and Hepatology, University of Illinois Peoria, Campus, OSF Saint Francis Medical Center, NE Glen Oak Ave, Peoria, IL 61637, United States. sonu.dhillon@osfhealthcare.org
Key Words	Hepatitis B vaccine; Non-responders; Intradermal vaccine; Adjuvants; Oral vaccine
Core Tip	Hepatitis B is a major global pandemic. Hepatitis B vaccine has been very effective in eradicating the disease from the world. Despite its efficacy, the standard vaccine fails to produce an immune response in 5% of immunocompetent individuals as well as indi-viduals with chronic diseases and immunosuppressed states. Different modalities have been used to produce an immune response in these non-responders. These include double dosing, more frequent dosing, intra?dermal vaccine, adjuvant vaccines and recombinant vaccine with variable efficacies. Despite these novel techniques there are still no official guidelines available to vaccinate non-responders.
Publish Date	2015-10-30 11:57
Citation	Walayat S, Ahmed Z, Martin D, Puli S, Cashman M, Dhillon S. Recent advances in vaccination of non-responders to standard dose hepatitis B virus vaccine. World J Hepatol 2015; 7(24): 2503-2509
URL	http://www.wjgnet.com/1948-5182/full/v7/i24/2503.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i24.2503

Full Article (PDF)	WJH-7-2503.pdf
Full Article (Word)	WJH-7-2503.doc
Manuscript File	22814-Review.doc
Answering Reviewers	22814-Answering reviewers.pdf
Audio Core Tip	22814-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22814-Conflict-of-interest statement.pdf
Copyright License Agreement	22814-Copyright assignment.pdf
Peer-review Report	22814-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	22814-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	22814-Scientific misconduct check.pdf
Scientific Editor Work List	22814-Scientific editor work list.pdf