Publication Name	World Journal of Gastroenterology
Manuscript ID	22820
Country	China

Received	2015-09-26 14:45
Peer-Review Started	2015-09-28 14:05
To Make the First Decision	2015-10-14 16:53
Return for Revision	2015-10-17 17:57
Revised
Second Decision	2016-01-22 14:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-30 17:20
Articles in Press	2016-01-30 17:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-01 09:14
Publish the Manuscript Online	2016-03-23 16:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Minireviews
Article Title	Liver transplantation for hepatocellular carcinoma beyond the Milan criteria: A review
Manuscript Source	Invited Manuscript
All Author List	Dong-Wei Xu, Ping Wan and Qiang Xia
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81472243
Corresponding Author	Dr. Qiang Xia, Department of Liver Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Dongfang Road, NO. 1630, Shanghai 200127, China. xiaqiang@shsmu.edu.cn
Key Words	Liver transplantation; Biological marker; Milan criteria; Hepatocellular carcinoma; Downstaging therapy; Adjuvant treatment
Core Tip	The Milan criteria (MC) were widely used in selecting liver transplantation (LT) candidates in hepatocellular carcinoma (HCC) patients. Because a substantial subset of HCC patients exceeding the MC and who would benefit from LT may be unnecessarily excluded from the waiting list, many extended criteria beyond the MC were raised. To predict the risk of tumor recurrence, some biological markers were also useful in HCC patients beyond the MC. Downstaging and adjuvant therapies are effective ways to reduce the tumor stage and the risk of recurrence. This article reviews the recent advances in LT for HCC beyond the MC.
Publish Date	2016-03-23 16:22
Citation	Xu DW, Wan P, Xia Q. Liver transplantation for hepatocellular carcinoma beyond the Milan criteria: A review. World J Gastroenterol 2016; 22(12): 3325-3334
URL	http://www.wjgnet.com/1007-9327/full/v22/i12/3325.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i12.3325

Full Article (PDF)	WJG-22-3325.pdf
Full Article (Word)	WJG-22-3325.doc
Manuscript File	22820-Review.doc
Answering Reviewers	22820-Answering reviewers.pdf
Audio Core Tip	22820-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22820-Conflict-of-interest statement.pdf
Copyright License Agreement	22820-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	22820-Grant application form.pdf
Non-Native Speakers of English Editing Certificate	22820-Language certificate.pdf
Peer-review Report	22820-Peer-review(s).pdf
Scientific Misconduct Check	22820-Scientific misconduct check.pdf
Scientific Editor Work List	22820-Scientific editor work list.pdf