Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	22845
Country	Türkiye

Received	2015-09-28 08:29
Peer-Review Started	2015-09-28 11:19
To Make the First Decision	2015-10-27 11:27
Return for Revision	2015-11-03 11:13
Revised	2015-11-22 19:30
Second Decision	2015-12-23 16:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-07 17:21
Articles in Press	2016-01-07 17:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-22 09:40
Publish the Manuscript Online	2016-01-28 14:57

ISSN	2219-2808 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Oral medications regarding their safety and efficacy in the management of patent ductus arteriosus
Manuscript Source	Invited Manuscript
All Author List	Mehmet Yekta Oncel and Omer Erdeve
Funding Agency and Grant Number
Corresponding Author	Omer Erdeve, MD, Department of Pediatrics, Division of Neonatology, Ankara University School of Medicine Children’s Hospital, Dögol Caddesi, 06100 Ankara, Turkey. omererdeve@yahoo.com
Key Words	Efficacy; Ibuprofen; Oral; Paracetamol; Patent ductus arteriosus; Preterm infant; Safety
Core Tip	Regarding to the management of patent ductus arteriosus (PDA) in preterm infants, neonatologists and cardiologists have not reached a consensus on which PDAs to treat, when to treat, and how to treat. Currently, ibuprofen seems to be the first choice due to its higher safety profile, as it is associated with fewer gastrointestinal and renal side effects when compared to indomethacin. PDA closure rates are better with oral than with intravenous ibuprofen. Recent studies suggest that paracetamol can be a medical alternative in the management of PDA with similar efficacy but lower side events than nonsteroidal anti-inflammatory drugs.
Publish Date	2016-01-28 14:57
Citation	Oncel MY, Erdeve O. Oral medications regarding their safety and efficacy in the management of patent ductus arteriosus. World J Clin Pediatr 2016; 5(1): 75-81
URL	http://www.wjgnet.com/2219-2808/full/v5/i1/75.htm
DOI	http://dx.doi.org/10.5409/wjcp.v5.i1.75

Full Article (PDF)	WJCP-5-75.pdf
Full Article (Word)	WJCP-5-75.doc
Manuscript File	22845-Review.docx
Answering Reviewers	22845-Answering reviewers.pdf
Audio Core Tip	22845-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22845-Conflict-of-interest statement.pdf
Copyright License Agreement	22845-Copyright assignment.pdf
Peer-review Report	22845-Peer-review(s).pdf
Scientific Misconduct Check	22845-Scientific misconduct check.pdf
Scientific Editor Work List	22845-Scientific editor work list.pdf