Publication Name	World Journal of Radiology
Manuscript ID	22873
Country	United States

Received	2015-09-29 08:30
Peer-Review Started	2015-10-02 15:15
To Make the First Decision	2015-10-27 11:31
Return for Revision	2015-11-04 15:48
Revised	2015-11-26 01:18
Second Decision	2015-12-28 14:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-01-11 15:51
Articles in Press	2016-01-11 15:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-07 13:29
Publish the Manuscript Online	2016-03-21 08:53

ISSN	1949-8470 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Angiographic and volumetric effects of mammalian target of rapamycin inhibitors on angiomyolipomas in tuberous sclerosis
Manuscript Source	Invited Manuscript
All Author List	Rahul A Sheth, Adam S Feldman, Elahna Paul, Elizabeth A Thiele and T Gregory Walker
Funding Agency and Grant Number
Corresponding Author	Rahul A Sheth, MD, Assistant Professor, Department of Interventional Radiology, MD Anderson Cancer Center, 1400 Pressler St., FCT14.6000, Houston, TX 77030, United States. rasheth@mdanderson.org
Key Words	Tuberous sclerosis; Angiomyolipoma; Sirolimus; Angiography; Transcatheter embolization; Interventional radiology; Mammalian target of rapamycin inhibition; Everolimus; Volumetrics
Core Tip	Pharmacologic management of tuberous sclerosis complex-associated angiomyolipomas with mammalian target of rapamycin inhibitors can provide substantial tumor volume reduction for the duration of the therapeutic course. This volume reduction impacts all three tissue compartments of the tumor. Unfortunately rebound growth involving all tissue compartments follows shortly after discontinuation of mammalian target of rapamycin (mTOR) inhibitor therapy. The addition of transarterial embolization to mTOR inhibition did not curtail the occurrence of rebound growth.
Publish Date	2016-03-21 08:53
Citation	Sheth RA, Feldman AS, Paul E, Thiele EA, Walker TG. Angiographic and volumetric effects of mammalian target of rapamycin inhibitors on angiomyolipomas in tuberous sclerosis. World J Radiol 2016; 8(3): 308-315
URL	http://www.wjgnet.com/1949-8470/full/v8/i3/308.htm
DOI	http://dx.doi.org/10.4329/wjr.v8.i3.308

Full Article (PDF)	WJR-8-308.pdf
Full Article (Word)	WJR-8-308.doc
Manuscript File	22873-Review.docx
Answering Reviewers	22873-Answering reviewers.pdf
Audio Core Tip	22873-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22873-Conflict-of-interest statement.pdf
Copyright License Agreement	22873-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	22873-Institutional review board statement.pdf
Peer-review Report	22873-Peer-review(s).pdf
Scientific Misconduct Check	22873-Scientific misconduct check.pdf
Scientific Editor Work List	22873-Scientific editor work list.pdf