Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	23083
Country	United States

Received	2015-10-20 13:22
Peer-Review Started	2015-10-21 09:58
To Make the First Decision	2015-11-24 14:16
Return for Revision	2015-11-27 16:47
Revised	2015-12-09 22:23
Second Decision	2016-02-22 11:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-03-09 12:17
Articles in Press	2016-03-09 12:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-14 16:04
Publish the Manuscript Online	2016-05-10 08:16

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Intensity modulated radiation therapy with simultaneous integrated boost based dose escalation on neoadjuvant chemoradiation therapy for locally advanced distal esophageal adenocarcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Ming Zeng, Fernando N Aguila, Taral Patel, Mark Knapp, Xue-Qiang Zhu, Xi-Lin Chen and Phillip D Price
Funding Agency and Grant Number
Corresponding Author	Ming Zeng, MD, PhD, Department of Radiation Oncology, Mount Carmel Health System, 3100 Plaza Properties Blvd, Columbus, OH 43219, United States. miller2002@yahoo.com
Key Words	Intensity modulated radiation therapy; Esophageal adenocarcinoma; Simultaneous integrated boost; Neoadjuvant chemoradiation; Dose escalation; Resection rate
Core Tip	There are more data supporting neoadjuvant chemoradiation for locally advanced esophageal cancer. The best regimen of neoadjuvant chemoradiation remains to be defined, current available data using three-dimensional vs intensity modulated radiation therapy deliver modest dose to downstage the tumor. In this report, we reviewed our experience using dose escalation technique to Gross Tumor Volume with compromising dose to organ at risk, the high R0 resection rate results suggest the feasibility of using this approach for future prospective study.
Publish Date	2016-05-10 08:16
Citation	Zeng M, Aguila FN, Patel T, Knapp M, Zhu XQ, Chen XL, Price PD. Intensity modulated radiation therapy with simultaneous integrated boost based dose escalation on neoadjuvant chemoradiation therapy for locally advanced distal esophageal adenocarcinoma. World J Gastrointest Oncol 2016; 8(5): 474-480
URL	http://www.wjgnet.com/1948-5204/full/v8/i5/474.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i5.474

Full Article (PDF)	WJGO-8-474.pdf
Full Article (Word)	WJGO-8-474.doc
Manuscript File	23083-Review.docx
Answering Reviewers	23083-Answering reviewers.pdf
Audio Core Tip	23083-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	23083-Conflict-of-interest statement.pdf
Copyright License Agreement	23083-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	23083-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	23083-Language certificate.pdf
Peer-review Report	23083-Peer-review(s).pdf
Scientific Misconduct Check	23083-Scientific misconduct check.pdf
Scientific Editor Work List	23083-Scientific editor work list.pdf