Publication Name	World Journal of Hepatology
Manuscript ID	2352
Country	Bangladesh

Received	2013-02-17 14:14
Peer-Review Started	2013-02-18 15:11
To Make the First Decision	2013-03-04 13:50
Return for Revision	2013-03-07 11:55
Revised	2013-04-30 15:24
Second Decision	2013-05-09 12:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-05-10 10:41
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-05-17 18:37
Publish the Manuscript Online	2013-05-27 12:24

ISSN	1948-5182 (online)
Open Access
Copyright
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Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Nonalcoholic steatohepatitis in nonalcoholic fatty liver disease patients of Bangladesh
Manuscript Source	Invited Manuscript
All Author List	Shahinul Alam, Sheikh Mohammad Noor-E-Alam, Ziaur Rahman Chowdhury, Mahabubul Alam and Jahangir Kabir
Funding Agency and Grant Number
Corresponding Author	Shahinul Alam, Associate Professor, Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, BSMMU, Shahbag, Dhaka 1000, Bangladesh. shahinul67@yahoo.com
Key Words	Fatty liver; Gamma-glutamyl transpeptidase; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Alanine aminotransferase; Obesity; Basal metabolic index
Core Tip	We have designed this study to explore the prevalence of and risk factors for nonalcoholic steatohepatitis (NASH) in nonalcoholic fatty liver disease patients. Other causes of liver disease were excluded. A total of 493 patients with sonographic evidence of fatty change were considered, and 177 of these patients were evaluated and confirmed by liver biopsy after making exclusions. Females were predominant (250, 57.0%). Central obesity was more prevalent among the patients compared with overall obesity. NASH was observed in 75 (42.4%) of the cases. The presence of diabetes and elevated gamma-glutamyl transpeptidase could differentiate NASH from simple steatosis. Serum alanine aminotransferase and aspartate aminotransferase could not be used to detect NASH.
Publish Date	2013-05-27 12:24
Citation	Alam S, Noor-E-Alam SM, Chowdhury ZR, Alam M, Kabir J. Nonalcoholic steatohepatitis in nonalcoholic fatty liver disease patients of Bangladesh. World J Hepatol 2013; 5(5): 281-287
URL	http://www.wjgnet.com/1948-5182/full/v5/i5/281.htm
DOI	http://dx.doi.org/10.4254/wjh.v5.i5.281

Full Article (PDF)	WJH-5-281.pdf
Manuscript File	2352-Review.doc
Answering Reviewers	2352-Answering reviewers.pdf
Copyright License Agreement	2352-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2352-Language certificate.pdf
Peer-review Report	2352-Peer reviews.pdf
Scientific Editor Work List	2352-Scientific editor work list.doc