Publication Name	World Journal of Transplantation
Manuscript ID	23527
Country	Spain

Received	2015-11-28 16:06
Peer-Review Started	2015-11-30 13:44
To Make the First Decision	2015-12-28 12:13
Return for Revision	2015-12-28 16:52
Revised	2016-01-11 06:35
Second Decision	2016-02-18 11:59
Accepted by Journal Editor-in-Chief	2016-02-19 23:30
Accepted by Executive Editor-in-Chief	2016-03-14 12:09
Articles in Press	2016-03-14 12:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-25 10:02
Publish the Manuscript Online	2016-06-22 16:18

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Allergy
Manuscript Type	Retrospective Cohort Study
Article Title	Single-lung transplantation in emphysema: Retrospective study analyzing survival and waiting list mortality
Manuscript Source	Invited Manuscript
All Author List	José M Borro, María Delgado, Elisabeth Coll and Salvador Pita
Funding Agency and Grant Number
Corresponding Author	José M Borro, MD, Department of Thoracic Surgery and Lung Transplantation, Corunna University Hospital, Xubias de Arriba 84, 15006 Corunna, Spain. jose.ma.borro.mate@sergas.es
Key Words	Lung transplantation; Single-lung; Survival; Complications; Emphysema; Double-lung
Core Tip	This is a retrospective and comparative study of 2 cohort of patients with advanced-stage emphysema who were performed uni or bilateral lung transplant. The results of this study support the realization of single-lung transplantation in most of the cases of emphysema because it is technically simpler, it has less risk of surgical sutures, and finally it has less immediate postoperative complications. Single and double lung transplantation has a similar long-term survival. Moreover, if a second transplant is needed in the long-term, the contralateral transplantation has the same initial transplant survi-val if the patient remains in a similar clinical situation. Survival Spanish national register does not show diffe-rence between the two techniques too, supporting the results of our relatively small series. This strategy of performing single lung transplantation in most of the cases of emphysema would encourage and enhance the use of donors thanks to the twining procedure, and would decrease mortality in the waiting list as shown in the National Transplant Organization patients analysed. Proper pre and postoperative prophylaxis and postoperative early extubation protocol is essential to achieve good results.
Publish Date	2016-06-22 16:18
Citation	Borro JM, Delgado M, Coll E, Pita S. Single-lung transplantation in emphysema: Retrospective study analyzing survival and waiting list mortality. World J Transplant 2016; 6(2): 347-355
URL	http://www.wjgnet.com/2220-3230/full/v6/i2/347.htm
DOI	http://dx.doi.org/10.5500/wjt.v6.i2.347

Full Article (PDF)	WJT-6-347.pdf
Full Article (Word)	WJT-6-347.doc
Manuscript File	23527-Review.docx
Answering Reviewers	23527-Answering reviewers.pdf
Audio Core Tip	23527-Audio core tip.mp3
Biostatistics Review Certificate	23527-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	23527-Conflict-of-interest statement.pdf
Copyright License Agreement	23527-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20151128070724.doc
Institutional Review Board Approval Form or Document	23527-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	23527-Language certificate.pdf
Peer-review Report	23527-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	23527-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	23527-Scientific misconduct check.pdf
Scientific Editor Work List	23527-Scientific editor work list.pdf