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4/29/2016 4:50:00 PM | Browse: 1878 | Download: 3791
Publication Name World Journal of Gastroenterology
Manuscript ID 23580
Country Finland
Received
2015-12-03 08:51
Peer-Review Started
2015-12-04 10:32
First Decision by Editorial Office Director
Return for Revision
2015-12-31 10:04
Revised
Publication Fee Transferred
Second Decision by Editor
2016-02-26 18:18
Second Decision by Editor-in-Chief
2016-02-26 18:30
Final Decision by Editorial Office Director
2016-03-02 10:33
Articles in Press
2016-03-02 10:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-04-05 15:45
Publish the Manuscript Online
2016-04-29 16:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Clinical Trials Study
Article Title Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis
Manuscript Source Unsolicited Manuscript
All Author List Tarja Ruuska, Peter Küster, Lena Grahnquist, Fredrik Lindgren and Anne Vibeke Wewer
Funding Agency and Grant Number
Funding Agency Grant Number
Otsuka Frankfurt Research Institute, Otsuka Pharmaceutical Europe Ltd.
Corresponding Author Tarja Ruuska, MD, Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland. tarja.ruuska@pshp.fi
Key Words Granulocyte-monocyte apheresis; Pediatric; Ulcerative colitis; Inflammatory bowel disease; Therapy; Steroids; Clinical trial
Core Tip For a considerable group of children with ulcerative colitis (UC), treatment options are limited especially after failure of conventional treatment. The ADAPT trial was designed to generate prospective cohort data on efficacy and safety levels in moderate active pediatric UC patients when treated with Adacolumn granulocyte, mono-cyte/macrophage adsorptive (GMA). The present data contribute to considering GMA apheresis as a therapeutic option in pediatric patients having failed first line therapy.
Publish Date 2016-04-29 16:50
Citation Ruuska T, Küster P, Grahnquist L, Lindgren F, Wewer AV. Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis. World J Gastroenterol 2016; 22(17): 4389-4396
URL http://www.wjgnet.com/1007-9327/full/v22/i17/4389.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i17.4389
Full Article (PDF) WJG-22-4389.pdf
Full Article (Word) WJG-22-4389.doc