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4/29/2016 4:50:00 PM | Browse: 641 | Download: 998
Publication Name World Journal of Gastroenterology
Manuscript ID 23580
Country/Territory Finland
Received
2015-12-03 08:51
Peer-Review Started
2015-12-04 10:32
To Make the First Decision
2015-12-31 08:50
Return for Revision
2015-12-31 10:04
Revised
Second Decision
2016-02-26 18:18
Accepted by Journal Editor-in-Chief
2016-02-26 18:30
Accepted by Company Editor-in-Chief
2016-03-02 10:33
Articles in Press
2016-03-02 10:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-04-05 15:45
Publish the Manuscript Online
2016-04-29 16:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Clinical Trials Study
Article Title Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis
Manuscript Source Unsolicited Manuscript
All Author List Tarja Ruuska, Peter Küster, Lena Grahnquist, Fredrik Lindgren and Anne Vibeke Wewer
Funding Agency and Grant Number
Funding Agency Grant Number
Otsuka Frankfurt Research Institute, Otsuka Pharmaceutical Europe Ltd.
Corresponding author Tarja Ruuska, MD, Department of Pediatrics, Tampere University Hospital, 33521 Tampere, Finland. tarja.ruuska@pshp.fi
Keywords Granulocyte-monocyte apheresis; Pediatric; Ulcerative colitis; Inflammatory bowel disease; Therapy; Steroids; Clinical trial
Core Tip For a considerable group of children with ulcerative colitis (UC), treatment options are limited especially after failure of conventional treatment. The ADAPT trial was designed to generate prospective cohort data on efficacy and safety levels in moderate active pediatric UC patients when treated with Adacolumn granulocyte, mono-cyte/macrophage adsorptive (GMA). The present data contribute to considering GMA apheresis as a therapeutic option in pediatric patients having failed first line therapy.
Publish Date 2016-04-29 16:50
Citation Ruuska T, Küster P, Grahnquist L, Lindgren F, Wewer AV. Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis. World J Gastroenterol 2016; 22(17): 4389-4396
Url http://www.wjgnet.com/1007-9327/full/v22/i17/4389.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i17.4389
Full Article (PDF) WJG-22-4389.pdf
Full Article (Word) WJG-22-4389.doc
Manuscript File 23580-Review.docx
Answering Reviewers 23580-Answering reviewers.pdf
Audio Core Tip 23580-Audio core tip.mp3
Biostatistics Review Certificate Biostatistics_Statement_20151202173721.pdf
Clinical Trial Registration Statement 23580-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 23580-Conflict-of-interest statement.pdf
Copyright License Agreement 23580-Copyright assignment.pdf
Data Sharing Statement 23580-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) 23580-Clinical trial registration statement.pdf
Institutional Review Board Approval Form or Document 23580-Institutional review board statement.pdf
Peer-review Report 23580-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 23580-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 23580-Scientific misconduct check.pdf
Scientific Editor Work List 23580-Scientific editor work list.pdf