BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/4/2016 10:08:00 AM | Browse: 933 | Download: 1767
 |
Received |
|
2015-12-29 09:35 |
|
Peer-Review Started |
|
2015-12-29 14:24 |
|
To Make the First Decision |
|
2016-01-28 15:05 |
|
Return for Revision |
|
2016-01-29 17:46 |
|
Revised |
|
2016-02-27 12:40 |
|
Second Decision |
|
2016-03-11 16:23 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Company Editor-in-Chief |
|
2016-03-18 17:43 |
|
Articles in Press |
|
2016-03-18 17:43 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2016-03-28 08:18 |
|
Typeset the Manuscript |
|
2016-04-07 09:05 |
|
Publish the Manuscript Online |
|
2016-05-04 10:08 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Peer-review started: February 25, 2016 |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Basic Study |
| Article Title |
Role of estrogen receptor β selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Cheng-Gang Zhang, Bin Zhang, Wen-Sheng Deng, Ming Duan, Wei Chen and Zhi-Yong Wu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation for the Youth of China |
81400630 |
|
| Corresponding Author |
Zhi-Yong Wu, MD, PhD, Department of Gastrointestinal Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, China. zhiyongwu1949@sina.com |
| Key Words |
Portal hypertension; Estrogen receptor; Rho-kinase signaling; Nitric oxide; Hepatic stellate cells |
| Core Tip |
Liver cirrhosis and portal hypertension (PHT) are subject to gender and estrogen levels. The aim of the present study was to investigate whether estrogen receptor β selective agonists could ameliorate intrahepatic resistance and mitigate PHT in rats with CCl4-induced cirrhosis, and uncover the underlying mechanism by investigating RhoA/ROCK and NO/PKG signaling. The authors propose that treatment with an estrogen receptor β selective agonist could improve cirrhotic PHT via regulating RhoA/ROCK and NO/PKG signaling. |
| Publish Date |
2016-05-04 10:08 |
| Citation |
Zhang CG, Zhang B, Deng WS, Duan M, Chen W, Wu ZY. Role of estrogen receptor β selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis. World J Gastroenterol 2016; 22(18): 4484-4500 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i18/4484.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i18.4484 |
© 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
