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Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 23688
Country Japan
Received
2015-12-10 17:29
Peer-Review Started
2015-12-11 13:16
To Make the First Decision
2016-01-13 09:02
Return for Revision
2016-01-13 13:29
Revised
2016-01-21 08:29
Second Decision
2016-02-22 13:30
Accepted by Journal Editor-in-Chief
2016-02-23 02:02
Accepted by Company Editor-in-Chief
2016-03-02 11:33
Articles in Press
2016-03-02 11:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-03-24 12:27
Publish the Manuscript Online
2016-05-12 16:59
ISSN 2150-5330 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Visualization of sphingolipids and phospholipids in the fundic gland mucosa of human stomach using imaging mass spectrometry
Manuscript Source Invited Manuscript
All Author List Nobuya Kurabe, Hisaki Igarashi, Ippei Ohnishi, Shogo Tajima, Yusuke Inoue, Yoshihiko Takahashi, Mitsutoshi Setou and Haruhiko Sugimura
Funding Agency and Grant Number
Corresponding Author Haruhiko Sugimura, MD, PhD, Professor, Department of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, Shizuoka 431-3192, Japan. hsugimur@hama-med.ac.jp
Key Words Imaging mass spectrometry; iMScope; Sphingomyelin; Phosphatidylcholine; Gastric mucosa
Core Tip Imaging mass spectrometry (MS) is a useful tool to survey the distribution of biomolecules in surgical specimens. Here we used the imaging MS apparatus named iMScope to identify the dominant molecules present in the human gastric mucosa near the fundic glands. Three major molecules with m/z 725.5, 780.5, and 782.5 detected in the gastric mucosa were identified as sphingomyelin (d18:1/16:0), phosphatidylcholine (PC) (16:0/18:2), and PC (16:0/18:1), respectively.
Publish Date 2016-05-12 16:59
Citation Kurabe N, Igarashi H, Ohnishi I, Tajima S, Inoue Y, Takahashi Y, Setou M, Sugimura H. Visualization of sphingolipids and phospholipids in the fundic gland mucosa of human stomach using imaging mass spectrometry. World J Gastrointest Pathophysiol 2016; 7(2): 235-241
URL http://www.wjgnet.com/2150-5330/full/v7/i2/235.htm
DOI http://dx.doi.org/10.4291/wjgp.v7.i2.235
Full Article (PDF) WJGP-7-235.pdf
Full Article (Word) WJGP-7-235.doc
Manuscript File 23688-Review.doc
Answering Reviewers 23688-Answering reviewers.pdf
Audio Core Tip 23688-Audio core tip.mp3
Biostatistics Review Certificate 23688-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 23688-Conflict-of-interest statement.pdf
Copyright License Agreement 23688-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 23688-Grant application form.docx
Institutional Animal Care and Use Committee Approval Form or Document 23688-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 23688-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 23688-Language certificate.pdf
Peer-review Report 23688-Peer-review(s).pdf
Scientific Misconduct Check 23688-Scientific misconduct check.pdf
Scientific Editor Work List 23688-Scientific editor work list.pdf