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Articles Published Processes
9/15/2014 5:55:00 PM | Browse: 1025 | Download: 1099
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Received |
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2013-02-19 11:02 |
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Peer-Review Started |
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2013-02-19 20:46 |
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To Make the First Decision |
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2013-03-11 15:12 |
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Return for Revision |
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2013-03-15 14:00 |
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Revised |
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2013-03-15 21:31 |
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Second Decision |
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2013-07-18 15:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-07-19 03:41 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-09-11 13:48 |
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Publish the Manuscript Online |
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2013-10-31 14:50 |
Category |
Immunology |
Manuscript Type |
Autobiography |
Article Title |
Aiming to immune elimination of ovarian cancer stem cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Jiabo Di, Tjitske Duiveman-de Boer, Carl G Figdor and Ruurd Torensma |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Netherlands Institute for Regenerative Medicine |
FES0908 |
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Corresponding Author |
Ruurd Torensma, PhD, Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Geert Grooteplein 28, GA 6525 Nijmegen, The Netherlands. r.torensma@ncmls.ru.nl |
Key Words |
Ovarian cancer; Cancer stem cell; Immune therapy; Immune suppression; Tumor microenvironment |
Core Tip |
Ovarian cancer harbors, at a low frequency, cancer stem cells. Those cancer stem cells express stem cell specific antigens. Natural immunity against those antigens exists but is hampered by the suppressive microenvironment that the tumor creates. Erasing this suppressive microenvironment will make immunological elimination of those cancer stem cells is an attractive treatment option. |
Publish Date |
2013-10-31 14:50 |
Citation |
Di J, Duiveman-de Boer T, Figdor CG, Torensma R. Aiming to immune elimination of ovarian cancer stem cells. World J Stem Cells 2013; 5(4): 149-162 |
URL |
http://www.wjgnet.com/1948-0210/full/v5/i4/149.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v5.i4.149 |
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