Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	23900
Country	United States

Received	2015-12-23 08:32
Peer-Review Started	2015-12-24 09:10
To Make the First Decision	2016-01-30 16:00
Return for Revision	2016-01-30 18:38
Revised	2016-02-02 10:39
Second Decision	2016-03-07 15:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-03-16 15:59
Articles in Press	2016-03-16 15:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-17 07:59
Publish the Manuscript Online	2016-06-01 11:12

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Genetic risks and familial associations of small bowel carcinoma
Manuscript Source	Invited Manuscript
All Author List	Santosh Shenoy
Funding Agency and Grant Number
Corresponding Author	Santosh Shenoy, MD, FACS, Department of Surgery, KCVA, University of Missouri at Kansas City, 4801 E Linwood Blvd, Kansas, MO 64128, United States. shenoy2009@hotmail.com
Key Words	Small intestinal adenocarcinoma; Genetic risks; Mutations; Signaling pathways; Surveillance
Core Tip	Adenocarcinoma of small intestine (SBA) is a relatively rare malignancy with poor outcomes due to delayed diagnosis. Certain genetic and familial diseases are associated with increased risks for SBA. These include Familial adenomatous polyposis, lynch syndromes, juvenile polyposis syndrome, Peutz-Jeghers syndrome, Crohn’s disease and celiac disease. We discuss the clinical implications of this aggressive cancer focusing on the genetic and familial associations, signaling mechanisms and available diagnostic modalities for surveillance.
Publish Date	2016-06-01 11:12
Citation	Shenoy S. Genetic risks and familial associations of small bowel carcinoma. World J Gastrointest Oncol 2016; 8(6): 509-519
URL	http://www.wjgnet.com/1948-5204/full/v8/i6/509.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i6.509

Full Article (PDF)	WJGO-8-509.pdf
Full Article (Word)	WJGO-8-509.doc
Manuscript File	23900-Review.docx
Answering Reviewers	23900-Answering reviewers.pdf
Audio Core Tip	23900-Audio core tip.wma
Conflict-of-Interest Disclosure Form	23900-Conflict-of-interest statement.pdf
Copyright License Agreement	23900-Copyright assignment.pdf
Peer-review Report	23900-Peer-review(s).pdf
Scientific Misconduct Check	23900-Scientific misconduct check.pdf
Scientific Editor Work List	23900-Scientific editor work list.pdf