BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/4/2016 10:08:00 AM | Browse: 1357 | Download: 2953
 |
Received |
|
2015-12-26 15:09 |
|
Peer-Review Started |
|
2015-12-28 10:49 |
 |
First Decision by Editorial Office Director |
|
|
|
Return for Revision |
|
2016-01-18 20:00 |
|
Revised |
|
2016-02-03 10:27 |
|
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2016-02-25 18:39 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2016-03-02 08:01 |
|
Articles in Press |
|
2016-03-02 08:01 |
|
Edit the Manuscript by Language Editor |
|
2016-03-30 16:29 |
|
Typeset the Manuscript |
|
2016-04-21 17:15 |
|
Publish the Manuscript Online |
|
2016-05-04 10:08 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Peer-review started: February 25, 2016 |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Basic Study |
| Article Title |
Elevated serum interleukin-38 level at baseline predicts virological response in telbivudine-treated patients with chronic hepatitis B
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Hong-Juan Wang, Yan-Fang Jiang, Xin-Rui Wang, Man-Li Zhang and Pu-Jun Gao |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Pu-Jun Gao, MD, PhD, Department of Hepatology, First Hospital of Jilin University, 71 Xinmin Street, Changchun 130021, Jilin Province, China. pujun-gao@163.com |
| Key Words |
Alanine aminotransferase; Aspartate amino¬transferase; Interleukin-6; Interleukin-12; Interleukin-38; Chronic hepatitis B; Primary non-response; Virological response |
| Core Tip |
This is the first study detailing kinetic changes in serum interleukin-38 (IL-38) levels during chronic hepatitis B (CHB). Higher pretreatment serum IL-38 levels are associated with a greater probability of virological response to telbivudine treatment. Elevated levels of serum IL-38 in untreated patients with CHB reflect ongoing liver injury, which is an indirect indicator of vigorous endogenous clearance of hepatitis B virus infection. Our findings suggest that clear signs of viral clearance at baseline may predict a favorable response to treatment of CHB using nucleoside analogs. |
| Publish Date |
2016-05-04 10:08 |
| Citation |
Wang HJ, Jiang YF, Wang XR, Zhang ML, Gao PJ. Elevated serum interleukin-38 level at baseline predicts virological response in telbivudine-treated patients with chronic hepatitis B. World J Gastroenterol 2016; 22(18): 4529-4537 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i18/4529.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i18.4529 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
