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8/1/2016 11:49:00 AM | Browse: 926 | Download: 1566
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Received |
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2016-01-03 17:44 |
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Peer-Review Started |
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2016-01-04 08:47 |
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To Make the First Decision |
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2016-02-26 18:11 |
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Return for Revision |
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2016-02-29 10:04 |
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Revised |
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2016-03-15 06:52 |
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Second Decision |
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2016-03-22 16:43 |
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Accepted by Journal Editor-in-Chief |
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2016-03-23 02:54 |
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Accepted by Company Editor-in-Chief |
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2016-04-06 13:48 |
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Articles in Press |
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2016-04-06 13:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-07-20 09:01 |
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Publish the Manuscript Online |
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2016-08-01 11:49 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Effects of aging on the architecture of the ileocecal junction in rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Maria Cícera de Brito, Renato Paulo Chopard, Diego Pulzatto Cury, Ii Sei Watanabe, Cristina Eusébio Mendes and Patricia Castelucci |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Patricia Castelucci, PhD, Associate Professor, Department of Anatomy/Biomedical Science Institute, University of São Paulo, R. Dr. Lineu Prestes 2415, São Paulo 05508-900, Brazil. pcastel@usp.br |
| Key Words |
Ileocecal junction; Elastic fibers; Collagen fibers; Aging; Rats |
| Core Tip |
The ileocolonic sphincter controls the forward and backward flow by integrating its motility with that of the distal ileum and proximal the ileocolonic sphincter controls the forward and backward flow by integrating its motility with that of the distal ileum and proxima. The ileocecal junction (ICJ) includes the muscle bundles in the terminal ileum, the intrinsic nerve plexus. The ICJ includes the muscle bundles in the terminal ileum, the intrinsic nerve plexus. Given the importance of knowing how the ICJ changes with age, the objective of this study was to characterize the morphological changes in the ICJ in rats aged 21 d and 2 years, using optical microscopy and electronic scanning and transmission methodologies. Additionally, the neurochemical characterization of the inhibitory neurons of the myenteric plexus, which are immunoreactive to the enzyme nitric oxide synthase, and the staining of the neuronal population were employed to identify immunoreactivity to HuC/D. |
| Publish Date |
2016-08-01 11:49 |
| Citation |
de Brito MC, Chopard RP, Cury DP, Watanabe IS, Mendes CE, Castelucci P. Effects of aging on the architecture of the ileocecal junction in rats. World J Gastrointest Pharmacol Ther 2016; 7(3): 416-427 |
| URL |
http://www.wjgnet.com/2150-5349/full/v7/i3/416.htm |
| DOI |
http://dx.doi.org/10.4292/wjgpt.v7.i3.416 |
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