Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	24070
Country	Sri Lanka

Received	2016-01-05 08:44
Peer-Review Started	2016-01-05 10:27
To Make the First Decision	2016-01-30 15:59
Return for Revision	2016-01-30 16:19
Revised	2016-02-11 20:20
Second Decision	2016-03-07 15:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-03-16 16:07
Articles in Press	2016-03-16 16:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-17 07:53
Publish the Manuscript Online	2016-06-01 11:12

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Colorectal cancer in the young, many questions, few answers
Manuscript Source	Invited Manuscript
All Author List	Kemal I Deen, Hiroshi Silva, Raeed Deen and Pramodh C Chandrasinghe
Funding Agency and Grant Number
Corresponding Author	Kemal I Deen, MD, MS, FRCS, FACRSI, FNat, Ac Sci, Consultant in Colon and Rectal Surgery, The Asiri Surgical Hospital, No.21 Kirimandala Mawatha, Colombo 11600, Sri Lanka. kemaldeen4@gmail.com
Key Words	Colon cancer; Young age; Rectal cancer; Colorectal cancer; Young patients; Survival; Early onset
Core Tip	This review of colorectal cancer in the young focuses on new data that reveal CRC to be more a left sided cancer than previously thought and the predicted rise by the year 2030. The article outlines the genetics of colorectal cancer (CRC) and discusses limitation in current knowledge in establishing a fingerprint for sporadic CRC. Aside from diet in its aetiology, luminal alkalinity and the colonic microbiome may be contributory and require further research. The review discusses the need for increased awareness of CRC in the young and the need for global consensus on screening young people at risk.
Publish Date	2016-06-01 11:12
Citation	Deen KI, Silva H, Deen R, Chandrasinghe PC. Colorectal cancer in the young, many questions, few answers. World J Gastrointest Oncol 2016; 8(6): 481-488
URL	http://www.wjgnet.com/1948-5204/full/v8/i6/481.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i6.481

Full Article (PDF)	WJGO-8-481.pdf
Full Article (Word)	WJGO-8-481.doc
Manuscript File	24070-Review.docx
Answering Reviewers	24070-Answering reviewers.pdf
Audio Core Tip	24070-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	24070-Conflict-of-interest statement.pdf
Copyright License Agreement	24070-Copyright assignment.pdf
Peer-review Report	24070-Peer-review(s).pdf
Scientific Misconduct Check	24070-Scientific misconduct check.pdf
Scientific Editor Work List	24070-Scientific editor work list.pdf