Publication Name	World Journal of Gastroenterology
Manuscript ID	24165
Country	Italy

Received	2016-01-11 08:44
Peer-Review Started	2016-01-13 08:36
To Make the First Decision	2016-02-18 16:55
Return for Revision	2016-02-20 15:23
Revised	2016-03-12 19:36
Second Decision	2016-04-22 10:28
Accepted by Journal Editor-in-Chief	2016-04-22 14:28
Accepted by Executive Editor-in-Chief	2016-05-04 18:22
Articles in Press	2016-05-04 18:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-02 08:45
Publish the Manuscript Online	2016-06-21 18:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Role and mechanisms of action of Escherichia coli Nissle 1917 in the maintenance of remission in ulcerative colitis patients: An update
Manuscript Source	Unsolicited Manuscript
All Author List	Franco Scaldaferri, Viviana Gerardi, Francesca Mangiola, Loris Riccardo Lopetuso, Marco Pizzoferrato, Valentina Petito, Alfredo Papa, Jovana Stojanovic, Andrea Poscia, Giovanni Cammarota and Antonio Gasbarrini
Funding Agency and Grant Number
Corresponding Author	Franco Scaldaferri, MD, PhD, Centre for the Research and Cure of Inflammatory Bowel Disease, UOC di Medicina Interna e Gastroenterologia, Institute of Medical Pathology, Catholic University of the Sacred Hearth, Fondazione Policlinico “A. Gemelli” Hospital, lgo Gemelli 8, 00168 Roma, Italy. francoscaldaferri@gmail.com
Key Words	Ulcerative colitis; Escherichia coli Nissle; Metanalysis; Probiotic; Randomized trial; Inflammatory bowel disease
Core Tip	Escherichia coli (E. coli) Nissle is a nonpa?thogenic Gram-negative strain used as a probiotic with very good quality paper assessing its bio-equivalence to mesalazine in maintaining remission in ulcerative colitis. Mechanisms of actions of this compound include immune-modulatory properties, reinforcement of intestinal barrier and inhibitory effect towards other pathogenic E. coli.
Publish Date	2016-06-21 18:11
Citation	Scaldaferri F, Gerardi V, Mangiola F, Lopetuso LR, Pizzoferrato M, Petito V, Papa A, Stojanovic J, Poscia A, Cammarota G, Gasbarrini A. Role and mechanisms of action of Escherichia coli nissle 1917 in the maintenance of remission in ulcerative colitis patients: An update. World J Gastroenterol 2016; 22(24): 5505-5511
URL	http://www.wjgnet.com/1007-9327/full/v22/i24/5505.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i24.5505

Full Article (PDF)	WJG-22-5505.pdf
Full Article (Word)	WJG-22-5505.doc
Manuscript File	24165-Review.docx
Answering Reviewers	24165-Answering reviewers.pdf
Audio Core Tip	24165-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	24165-Conflict-of-interest statement.pdf
Copyright License Agreement	24165-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	24165-Language certificate.pdf
Peer-review Report	24165-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	24165-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	24165-Scientific misconduct check.pdf
Scientific Editor Work List	24165-Scientific editor work list.pdf