BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/19/2016 2:49:00 PM | Browse: 908 | Download: 1315
Publication Name World Journal of Gastroenterology
Manuscript ID 24212
Country/Territory Hungary
Received
2016-01-13 08:57
Peer-Review Started
2016-01-15 09:26
To Make the First Decision
2016-02-18 16:55
Return for Revision
2016-02-20 15:36
Revised
2016-03-05 17:47
Second Decision
2016-03-31 10:23
Accepted by Journal Editor-in-Chief
2016-04-01 20:37
Accepted by Company Editor-in-Chief
2016-04-07 15:53
Articles in Press
2016-04-07 15:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-05-05 10:54
Publish the Manuscript Online
2016-05-19 14:49
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Basic Study
Article Title Immunological changes in different patient populations with chronic hepatitis C virus infection
Manuscript Source Invited Manuscript
All Author List Laszlo Szereday, Matyas Meggyes, Melinda Halasz, Julia Szekeres-Bartho, Alajos Par and Gabriella Par
Funding Agency and Grant Number
Funding Agency Grant Number
Hungarian National Research Fund OTKA K81454
Hungarian National Research Fund OTKA K104960
Liver Research Foundation (Pécs), United European Gastroenterology Federation
Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences
Corresponding Author Laszlo Szereday, MD, PhD, Associate Professor of Microbiology, Department of Medical Microbiology and Immunology, University of Pecs, Clinical Centre, 7624 Pecs, Hungary. szereday.laszlo@pte.hu
Key Words Hepatitis C; Natural killer cell; NKG2D; Cytotoxicity; Cytokine
Core Tip The host immune response to hepatitis C virus (HCV) involves both innate and adaptive arms of the immune system. natural killer (NK) cells are key components of the innate antiviral immune response. To better characterize the immune defects underlying chronic viral persistence, we focus our analysis on killer inhibitory and activating receptor expression in patients with chronic HCV infection with elevated alanine aminotransferase (ALT) and also in patients with HCV carriers with persistently normal ALT. Decreased NKG2D and CD160 activating receptor expression and increased KIR2DL3 inhibitory receptor expression by NK and cytotoxic T cells in patients with chronic hepatitis C contributing to defective cellular immune functions.
Publish Date 2016-05-19 14:49
Citation Szereday L, Meggyes M, Halasz M, Szekeres-Bartho J, Par A, Par G. Immunological changes in different patient populations with chronic hepatitis C virus infection. World J Gastroenterol 2016; 22(20): 4848-4859
URL http://www.wjgnet.com/1007-9327/full/v22/i20/4848.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i20.4848
Full Article (PDF) WJG-22-4848.pdf
Full Article (Word) WJG-22-4848.doc
Manuscript File 24212-Review.doc
Answering Reviewers 24212-Answering reviewers.pdf
Audio Core Tip 24212-Audio core tip.mp3
Biostatistics Review Certificate 24212-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 24212-Conflict-of-interest statement.pdf
Copyright License Agreement 24212-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 24212-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 24212-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 24212-Language certificate.pdf
Peer-review Report 24212-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 24212-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 24212-Scientific misconduct check.pdf
Scientific Editor Work List 24212-Scientific editor work list.pdf