Publication Name	World Journal of Gastroenterology
Manuscript ID	24259
Country	China

Received	2016-01-25 08:24
Peer-Review Started	2016-01-25 10:05
To Make the First Decision	2016-02-18 11:48
Return for Revision	2016-02-19 11:05
Revised	2016-02-26 00:00
Second Decision	2016-03-11 14:17
Accepted by Journal Editor-in-Chief	2016-03-11 18:15
Accepted by Executive Editor-in-Chief	2016-03-18 17:28
Articles in Press	2016-03-18 17:29
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-03-29 10:28
Typeset the Manuscript	2016-04-06 12:23
Publish the Manuscript Online	2016-04-19 09:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Qian Zhu, Jun Wang, Xu-Feng Guo, Zhou Liu and Wei-Guo Dong
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81372551
Corresponding Author	Dr. Wei-guo Dong, Professor, Depart­ment of Gastroenterology, Renmin Hospital of Wuhan University, Key Laboratory of Hubei Province for Digestive System Disease, Hubei Zhang Road, Wuhan 430060, Hubei Province, China. dwg@whu.edu.cn
Key Words	Thymoquinone; Gastric cancer; STAT3; Proliferation; Apoptosis
Core Tip	Thymoquinone (TQ) has been demonstrated to exert biological activity in gastric cancer. However, the specific mechanism of TQ in gastric cancer has not been examined. In order to elucidate the mechanism of TQ-induced apoptosis in human gastric cancer cells, we investigated the effects of TQ on signal transducer and activator of transcription (STAT)3 and its related pathway in vitro and in vivo.
Publish Date	2016-04-19 09:42
Citation	Zhu WQ, Wang J, Guo XF, Liu Z, Dong WG. Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro. World J Gastroenterol 2016; 22(16): 4149-4159
URL	http://www.wjgnet.com/1007-9327/full/v22/i16/4149.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i16.4149

Full Article (PDF)	WJG-22-4149.pdf
Full Article (Word)	WJG-22-4149.doc
Manuscript File	24259-Review.docx
Answering Reviewers	24259-Answering reviewers.pdf
Audio Core Tip	24259-Audio core tip.mp3
Biostatistics Review Certificate	24259-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24259-Conflict-of-interest statement.pdf
Copyright License Agreement	24259-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	24259-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	24259-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	24259-Institutional review board statement.pdf
Peer-review Report	24259-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	24259-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	24259-Scientific misconduct check.pdf
Scientific Editor Work List	24259-Scientific editor work list.pdf