Publication Name	World Journal of Gastroenterology
Manuscript ID	24361
Country	United States

Received	2016-01-19 17:10
Peer-Review Started	2016-01-19 17:33
To Make the First Decision	2016-03-07 09:11
Return for Revision	2016-03-07 11:00
Revised	2016-03-16 04:21
Second Decision	2016-03-24 11:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-03-30 16:48
Articles in Press	2016-03-30 16:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-06 10:46
Publish the Manuscript Online	2016-05-17 10:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Allergy
Manuscript Type	Retrospective Cohort Study
Article Title	Veterans health administration hepatitis B testing and treatment with anti-CD20 antibody administration
Manuscript Source	Invited Manuscript
All Author List	Christine M Hunt, Lauren A Beste, Elliott Lowy, Ayako Suzuki, Cynthia A Moylan, Hans L Tillmann, George N Ioannou, Joseph K Lim, Michael J Kelley and Dawn Provenzale
Funding Agency and Grant Number	Funding Agency Grant Number Veterans Affairs (VA) Cooperative Studies Program Epidemiology Center-Durham, the Puget Sound VA Health Care System, and the VA Office of Public Health and Human Health Pathogens (partly)
Corresponding Author	Christine M Hunt, MD, MPH, Adjunct Associate Professor of Medicine, Department of Medicine, Duke University School of Medicine, Duke University, 00550 Hospital South, Durham, NC 27710, United States. christine.hunt@va.gov
Key Words	Hepatitis B; Hepatitis B reactivation; Anti-CD20 antibody; Rituximab; Lymphoma; Chemotherapy; Hepatitis B antivirals; Vaccination; Veteran
Core Tip	Prior to anti-CD20 antibody (Ab) treatment in 2014, 61%-73% of 19304 Veterans had hepatitis B virus (HBV) tests. Of these, 11% tested were positive for hepatitis B surface antigen or core antibody and at risk for reactivation; ≤ 37% of these HBV+ patients received HBV antivirals during anti-CD20 Ab and follow-up. HBV+ patients had significantly higher hepatitis rates than HBV-. Among pretreatment HBV- patients, about 1 in 300 tested suffered acute hepatitis during anti-CD20 Ab and 12 mo follow-up. Electronic health record algorithms to increase HBV testing, antiviral use and vaccination will likely improve outcomes with anti-CD20 Ab treatment.
Publish Date	2016-05-17 10:45
Citation	Hunt CM, Beste LA, Lowy E, Suzuki A, Moylan CA, Tillmann HL, Ioannou GN, Lim JK, Kelley MJ, Provenzale D. Veterans health administration hepatitis B testing and treatment with anti-CD20 antibody administration. World J Gastroenterol 2016; 22(19): 4732-4740
URL	http://www.wjgnet.com/1007-9327/full/v22/i19/4732.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i19.4732

Full Article (PDF)	WJG-22-4732.pdf
Full Article (Word)	WJG-22-4732.doc
Manuscript File	24361-Review.doc
Answering Reviewers	24361-Answering reviewers.pdf
Audio Core Tip	24361-Audio core tip.mp3
Biostatistics Review Certificate	24361-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24361-Conflict-of-interest statement.pdf
Copyright License Agreement	24361-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	24361-Grant application form(s).pdf
Institutional Review Board Approval Form or Document	24361-Institutional review board statement.pdf
Peer-review Report	24361-Peer-review(s).pdf
Scientific Misconduct Check	24361-Scientific misconduct check.pdf
Scientific Editor Work List	24361-Scientific editor work list.pdf