Publication Name	World Journal of Orthopedics
Manuscript ID	24413
Country	Germany

Received	2016-01-22 10:52
Peer-Review Started	2016-01-22 18:39
To Make the First Decision	2016-02-29 15:11
Return for Revision	2016-03-01 16:26
Revised	2016-03-26 04:43
Second Decision	2016-04-26 16:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-05-11 16:06
Articles in Press	2016-05-11 16:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-06-28 17:32
Publish the Manuscript Online	2016-07-10 19:25

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Orthopedics
Manuscript Type	Basic Study
Article Title	Evaluation of bone remodeling in regard to the age of scaphoid non-unions
Manuscript Source	Invited Manuscript
All Author List	Susanne Rein, Uwe Hanisch, Hans-Eberhard Schaller, Hans Zwipp, Stefan Rammelt and Stefan Weindel
Funding Agency and Grant Number
Corresponding Author	Susanne Rein, MD, PhD, Department of Plastic and Hand Surgery, Burn Unit, Trauma Center Bergmannstrost, Merseburger Straße 165, 06112 Halle (Saale), Germany. susanne.rein@web.de
Key Words	Bone remodeling; Histology; Immunohis­tological staining; Scaphoid non-union; Scaphoid; Wrist joint
Core Tip	The bone remodeling in regard to the age of scaphoid non-union is investigated with immunohis-tochemistry. Multinuclear osteoclasts showed a signifi-cant decrease in relation of the age of scaphoid non-union, but smoking and the age of the patients had no influence on bone remodeling. Most of the immunhis-tochemical findings of bone remodeling do not correlate with the age of the scaphoid non-unions, which indicates a permanent imbalance of bone formation and resorption.
Publish Date	2016-07-10 19:25
Citation	Rein S, Hanisch U, Schaller HE, Zwipp H, Rammelt S, Weindel S. Evaluation of bone remodeling in regard to the age of scaphoid non-unions. World J Orthop 2016; 7(7): 418-425
URL	http://www.wjgnet.com/2218-5836/full/v7/i7/418.htm
DOI	http://dx.doi.org/10.5312/wjo.v7.i7.418

Full Article (PDF)	WJO-7-418.pdf
Full Article (Word)	WJO-7-418.doc
Manuscript File	24413-Review.docx
Answering Reviewers	24413-Answering reviewers.pdf
Audio Core Tip	24413-Audio core tip.mp3
Biostatistics Review Certificate	Biostatistics_Statement_20160121193059.doc
Conflict-of-Interest Disclosure Form	24413-Conflict-of-interest statement.pdf
Copyright License Agreement	24413-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	24413-Institutional review board statement.pdf
Peer-review Report	24413-Peer-review(s).pdf
Scientific Misconduct Check	24413-Scientific misconduct check.pdf
Scientific Editor Work List	24413-Scientific editor work list.pdf