BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/2/2016 3:32:00 PM | Browse: 1216 | Download: 2399
 |
Received |
|
2016-01-25 11:04 |
|
Peer-Review Started |
|
2016-01-25 11:06 |
|
To Make the First Decision |
|
2016-02-18 11:34 |
|
Return for Revision |
|
2016-02-18 12:21 |
|
Revised |
|
2016-03-02 22:09 |
|
Second Decision |
|
2016-03-11 16:24 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2016-03-18 17:47 |
|
Articles in Press |
|
2016-03-18 17:47 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2016-04-21 14:25 |
|
Typeset the Manuscript |
|
2016-05-12 16:56 |
|
Publish the Manuscript Online |
|
2016-06-02 15:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
|
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Chitooligosaccharides promote radiosensitivity in colon cancer line SW480
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fu-Shi Han, Shi-Jie Yang, Mou-Bin Lin, Ying-Qun Chen, Ping Yang and Jin-Ming Xu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81272480 |
|
| Corresponding Author |
Jin-Ming Xu, Chief Physician, Department of Imaging, Tongji University Affiliated Yangpu Hospital, No. 450 Tengyue Road, Shanghai 200090, China. xu10611@hotmail.com
|
| Key Words |
Chitooligosaccharides; Cancer of colon; Radiotherapy; Radiosensitization; Apoptosis; Cell cycle |
| Core Tip |
In this study, the colorectal cancer cell line SW480 that is homologous with colon-rectum was used as the research tool. It was confirmed that chitooligosaccharides (COS) not only directly blocked SW480 cell proliferation, but also enhanced radiotherapy effects. Furthermore, COS induced a large amount of SW480 cell apoptosis, and induced a large number of cells to remain in the G2/M phase with radiation-sensitive killing effect. Thus, the sensitivity of SW480 cells to radiation was effectively enhanced 1.39 times. This is beneficial for the therapeutic effect.
|
| Publish Date |
2016-06-02 15:26 |
| Citation |
Han FS, Yang SJ, Lin MB, Chen YQ, Yang P, Xu JM. Chitooligosaccharides promote radiosensitivity in colon cancer line SW480. World J Gastroenterol 2016; 22(22): 5193-5200 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i22/5193.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i22.5193 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
