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5/12/2016 10:38:00 AM | Browse: 1029 | Download: 1533
Publication Name World Journal of Hepatology
Manuscript ID 24505
Country/Territory Pakistan
Received
2016-01-26 10:15
Peer-Review Started
2016-01-27 09:07
To Make the First Decision
2016-03-09 10:02
Return for Revision
2016-03-10 09:17
Revised
2016-03-13 22:53
Second Decision
2016-04-07 12:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-04-18 11:45
Articles in Press
2016-04-18 11:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-04-19 16:11
Publish the Manuscript Online
2016-05-12 10:37
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Clinical Trial
Article Title Co-treatment with pegylated interferon alfa-2a and entecavir for hepatitis D: A randomized trial
Manuscript Source Invited Manuscript
All Author List Zaigham Abbas, Mohammad Sadik Memon, Muhammad Amir Umer, Minaam Abbas and Lubna Shazi
Funding Agency and Grant Number
Corresponding Author Dr. Zaigham Abbas, FCPS, FRCP, Department of Gastroenterology, Ziauddin University Hospital, Shahrah-e-Ghalib, Karachi 74400, Pakistan. drzabbas@gmail.com
Key Words Hepatitis D; Entecavir; Hepatitis B surface antigen; Pegylated interferon; Hepatitis D virus RNA; Treatment
Core Tip Chronic hepatitis D is a difficult to treat infec-tion. Six months post treatment response is seen only in one quarter of the patients treated with pegy-lated interferon alfa (PEG-IFNα). In an attempt to improve the response of PEG-IFN, we combined entecavir. This is the first study to evaluate the efficacy of PEG-IFN with entecavir compared to PEG-IFN alone for the treatment of hepatitis D infection. Our study showed that the com-bination treatment did not have any additional benefit in terms of hepatitis D virus RNA suppression and hepatitis B surface antigen reduction as compared to PEG-IFN alone.
Publish Date 2016-05-12 10:37
Citation Abbas Z, Memon MS, Umer MA, Abbas M, Shazi L. Co-treatment with pegylated interferon alfa-2a and entecavir for hepatitis D: A randomized trial. World J Hepatol 2016; 8(14): 625-631
URL http://www.wjgnet.com/1948-5182/full/v8/i14/625.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i14.625
Full Article (PDF) WJH-8-625.pdf
Full Article (Word) WJH-8-625.doc
Manuscript File 24505-Review.docx
Answering Reviewers 24505-Answering reviewers.pdf
Audio Core Tip 24505-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 24505-Conflict-of-interest statement.pdf
Copyright License Agreement 24505-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160125155135.pdf
Institutional Review Board Approval Form or Document 24505-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 24505-Language certificate.pdf
Peer-review Report 24505-Peer-review(s).pdf
Scientific Misconduct Check 24505-Scientific misconduct check.pdf
Scientific Editor Work List 24505-Scientific editor work list.pdf